Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.43 |
| ▸ | KDM4A | O75164 | 2/20 | 0.43 |
| ▸ | KDM5A | P29375 | 2/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.39 |
| ▸ | MAP3K5 | Q99683 | 11/20 | 0.38 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28652012 | 0.88 | KDM4C (0.55) | KDM4CKDM4AKDM5AKDM5BPIK3CA | |
| SCHEMBL28646401 | 0.84 | KDM4C (0.46) | KDM4CKDM4AKDM5AKDM5BMAP3K5 | |
| SCHEMBL28646403 | 0.79 | MAP3K5 (0.51) | MAP3K5 | |
| SCHEMBL20750911 | 0.79 | MAP3K5 (0.41) | MAP3K5 | |
| SCHEMBL28643374 | 0.77 | MAP3K5 (0.52) | MAP3K5 | |
| SCHEMBL28668610 | 0.76 | MAP3K5 (0.53) | MAP3K5 | |
| SCHEMBL28848700 | 0.76 | MAP3K5 (0.35) | MAP3K5PDE10A | |
| SCHEMBL28648124 | 0.74 | MAP3K5 (0.42) | MAP3K5 | |
| SCHEMBL28658684 | 0.74 | MAP3K5 (0.40) | MAP3K5 | |
| SCHEMBL28643386 | 0.73 | MAP3K5 (0.38) | MAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109400625-B | Fused bicyclic compound and application thereof in medicine | 广东东阳光药业有限公司 | 2021-11-12 | — | — | CN | disclosed |