Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | OGA | O60502 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PDE2A | O00408 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17206376 | 0.89 | SMN1; SMN2 (0.56) | SMN1; SMN2GAALMNAOGAL3MBTL1 | |
| SCHEMBL3085718 | 0.88 | SMN1; SMN2 (0.57) | SMN1; SMN2GAALMNAOGAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL4590631 | 0.85 | SMN1; SMN2 (0.61) | SMN1; SMN2GAALMNAOGAL3MBTL1 | |
| SCHEMBL3082241 | 0.80 | CNR2 (0.55) | SMN1; SMN2GAALMNAOGAL3MBTL1 | |
| SCHEMBL28120419 | 0.79 | ALDH1A1 (0.47) | SMN1; SMN2GAALMNAL3MBTL1ALDH1A1 | |
| SCHEMBL28120087 | 0.78 | ALDH1A1 (0.50) | SMN1; SMN2GAALMNAL3MBTL1ALDH1A1 | |
| SCHEMBL4590541 | 0.77 | ALDH1A1 (0.64) | SMN1; SMN2GAALMNAALDH1A1KMT2A | |
| SCHEMBL15714866 | 0.77 | ALDH1A1 (0.53) | SMN1; SMN2GAALMNAL3MBTL1ALDH1A1 | |
| SCHEMBL28975291 | 0.77 | NPC1 (0.59) | SMN1; SMN2GAALMNAOGAALDH1A1 | |
| SCHEMBL470928 | 0.76 | SMN1; SMN2 (0.58) | SMN1; SMN2GAALMNAOGAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107001339-A | Novel compounds | 特殊治疗有限公司 | 2017-08-01 | — | — | CN | disclosed |