Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29261360 | 0.98 | POLB (0.41) | ALDH1A1POLBSMN1; SMN2LMNAATM | |
| SCHEMBL14999309 | 0.85 | ALDH1A1 (0.44) | ALDH1A1POLBSMN1; SMN2LMNAATM | |
| SCHEMBL17093002 | 0.84 | SMN1; SMN2 (0.46) | ALDH1A1POLBSMN1; SMN2LMNAATM | |
| SCHEMBL21670363 | 0.83 | ALDH1A1 (0.42) | ALDH1A1POLBSMN1; SMN2LMNAATM | |
| SCHEMBL22978725 | 0.83 | ALDH1A1 (0.45) | ALDH1A1POLBSMN1; SMN2LMNAATM | |
| SCHEMBL16684932 | 0.83 | POLB (0.42) | ALDH1A1POLBSMN1; SMN2LMNAATM | |
| SCHEMBL13034371 | 0.82 | ALDH1A1 (0.42) | ALDH1A1POLBSMN1; SMN2LMNAATM | |
| SCHEMBL27721600 | 0.82 | SMN1; SMN2 (0.46) | ALDH1A1POLBSMN1; SMN2LMNAATM | |
| SCHEMBL16965305 | 0.80 | POLB (0.52) | ALDH1A1POLBSMN1; SMN2LMNAATM | |
| SCHEMBL20293774 | 0.80 | ALDH1A1 (0.42) | ALDH1A1POLBSMN1; SMN2ATMTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025244956-A1 | METHODS OF MANUFACTURING DANICAMTIV | MyoKardia, Inc. (US) | 2025-11-27 | — | — | WO | disclosed |
| CN-105073741-B | Phthalazinones and isoquinolinones as ROCK inhibitors | 百时美施贵宝公司 | 2017-08-08 | — | — | CN | disclosed |