Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL28848798

CCCCCN1C(=O)c2ccccc2S1(=O)=O.S

nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 7/20 0.97
CA12 O43570 6/20 0.97
ALDH1A1 P00352 1/20 0.66
CYP2C19 P33261 1/20 0.66
CA2 P00918 2/20 0.63
HDAC1 Q13547 1/20 0.60
HDAC2 Q92769 1/20 0.60
ACHE P22303 2/20 0.60
ELANE P08246 3/20 0.59
DRD2 P14416 3/20 0.59
DRD4 P21917 1/20 0.59
DRD5 P21918 1/20 0.59
DRD3 P35462 1/20 0.59
HTR1A P08908 2/20 0.57
HTR2A P28223 2/20 0.57
HTR7 P34969 2/20 0.57
HTR6 P50406 2/20 0.57
HPGD P15428 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1758371 0.98 CA9 (1.00) CA9CA12ALDH1A1CYP2C19CA2
SCHEMBL14560535 0.97 CA9 (0.97) CA9CA12ALDH1A1CYP2C19CA2
SCHEMBL29621871 0.97 CA9 (0.97) CA9CA12ALDH1A1CYP2C19CA2
SCHEMBL7903703 0.94 CA9 (1.00) CA9CA12ALDH1A1CYP2C19CA2
SCHEMBL698407 0.87 CA9 (1.00) CA9CA12ALDH1A1CYP2C19CA2
SCHEMBL12827008 0.86 CA9 (0.78) CA9CA12ALDH1A1CYP2C19CA2
SCHEMBL6324557 0.83 CA9 (0.73) CA9CA12ALDH1A1CYP2C19CA2
SCHEMBL17329453 0.83 CA9 (0.73) CA9CA12CA2HDAC1HDAC2
SCHEMBL9826952 0.83 CA9 (0.73) CA9CA12ALDH1A1CYP2C19CA2
SCHEMBL27183193 0.83 CA9 (0.74) CA9CA12ALDH1A1CYP2C19CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109776355-A The preparation method of smooth hypotensor important intermediate 2- cyano-the 4 '-bromomethylbiphenyl of one seed sand 浙江工业大学 2019-05-21 CN disclosed
CN-105295747-B A kind of lubricating type thread locking sealing anaerbic adhesive and preparation method thereof 湖北回天新材料股份有限公司 2017-10-31 CN disclosed