Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 8/20 | 1.00 |
| ▸ | CA12 | O43570 | 8/20 | 1.00 |
| ▸ | CA2 | P00918 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | ELANE | P08246 | 3/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.58 |
| ▸ | DRD4 | P21917 | 1/20 | 0.58 |
| ▸ | DRD5 | P21918 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1758371 | 0.95 | CA9 (1.00) | CA9CA12CA2ALDH1A1CYP2C19 | |
| Hydrogen Sulfide SCHEMBL28848798 | 0.94 | CA9 (0.97) | CA9CA12CA2ALDH1A1CYP2C19 | |
| SCHEMBL14560535 | 0.94 | CA9 (0.97) | CA9CA12CA2ALDH1A1CYP2C19 | |
| SCHEMBL29621871 | 0.94 | CA9 (0.97) | CA9CA12CA2ALDH1A1CYP2C19 | |
| SCHEMBL698407 | 0.90 | CA9 (1.00) | CA9CA12CA2ALDH1A1CYP2C19 | |
| SCHEMBL12827008 | 0.86 | CA9 (0.78) | CA9CA12CA2ALDH1A1CYP2C19 | |
| SCHEMBL27183193 | 0.86 | CA9 (0.74) | CA9CA12CA2ALDH1A1CYP2C19 | |
| SCHEMBL7932914 | 0.85 | CA9 (0.74) | CA9CA12CA2ALDH1A1CYP2C19 | |
| SCHEMBL17372964 | 0.84 | CA9 (0.72) | CA9CA12CA2ALDH1A1CYP2C19 | |
| SCHEMBL8973563 | 0.84 | CA9 (0.72) | CA9CA12CA2ALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112608702-A | Double-component acrylic acid modified epoxy adhesive and preparation process thereof | 迪马新材料科技（苏州）有限公司 | 2021-04-06 | — | — | CN | claimed |
| CN-103897099-B | A kind of filter pressing lightweight seepy material and preparation method thereof | 中科院广州化学有限公司南雄材料生产基地 | 2016-08-10 | — | — | CN | claimed |
| US-6197854-B1 | Polycarbonate composition resistant to gamma radiation | BAYER CORPORATION | 2001-03-06 | — | — | US | claimed |
| US-5952351-A | DERIVATIVES OF 1,1,3-TRIOXO-2-((2-OXOBENZIMIDAZOLIN- OR BENZOXAZOLIN-2-YL)-PIPERIDIN-4,1-YLENE-)-1,2-BENZISOTHIAZOLE; TREATMENT OF BENIGN PROSTATIC HYPERPLASIA; SELECTIVE RELAXATION OF SMOOTH MUSCLE WITHOUT INDUCING HYPOTENSION | MERCK & CO., INC. (US) | 1999-09-14 | — | — | US | claimed |
| EP-0831823-A4 | ALPHA 1a ADRENERGIC RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 1998-10-21 | — | — | EP | claimed |
| EP-0812196-A4 | ALPHA 1a ADRENERGIC RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 1998-05-20 | — | — | EP | claimed |
| EP-0831823-A1 | ALPHA 1a ADRENERGIC RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 1998-04-01 | — | — | EP | claimed |
| EP-0812196-A1 | ALPHA 1a ADRENERGIC RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 1997-12-17 | — | — | EP | claimed |
| US-5620993-A | Alpha-1a adrenergic receptor antagonists | MERCK & CO., INC. (US) | 1997-04-15 | — | — | US | claimed |
| WO-1996040135-A1 | ALPHA 1a ADRENERGIC RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1996-12-19 | — | — | WO | claimed |
| WO-1996025934-A1 | ALPHA 1a ADRENERGIC RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1996-08-29 | — | — | WO | claimed |
| CN-113995844-A | A topical Chinese medicinal ointment for promoting absorption, and its preparation method | 深圳市明臣眼科医疗有限公司 | 2022-02-01 | — | — | CN | disclosed |
| CN-113694151-A | Externally applied traditional Chinese medicine ointment for treating amblyopia and preparation method thereof | 深圳市明臣眼科医疗有限公司 | 2021-11-26 | — | — | CN | disclosed |
| CN-112608702-A | Double-component acrylic acid modified epoxy adhesive and preparation process thereof | 迪马新材料科技（苏州）有限公司 | 2021-04-06 | — | — | CN | disclosed |
| US-9627217-B2 | Silicon-containing EUV resist underlayer film-forming composition including additive | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-04-18 | — | — | US | disclosed |
| US-5620993-A | Alpha-1a adrenergic receptor antagonists | MERCK & CO., INC. (US) | 1997-04-15 | — | — | US | disclosed |
| EP-0755392-A1 | ALPHA1C ADRENERGIC RECEPTOR ANTAGONISTS | MERCK & CO. INC. (US) | 1997-01-29 | — | — | EP | disclosed |
| WO-1996040135-A1 | ALPHA 1a ADRENERGIC RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1996-12-19 | — | — | WO | disclosed |
| WO-1996025934-A1 | ALPHA 1a ADRENERGIC RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1996-08-29 | — | — | WO | disclosed |
| WO-1995028397-A1 | ALPHA1C ADRENERGIC RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1995-10-26 | — | — | WO | disclosed |