Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 5/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.38 |
| ▸ | PDE2A | O00408 | 2/20 | 0.37 |
| ▸ | PDE1A | P54750 | 1/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.37 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25776011 | 0.74 | PRKDC (0.47) | PIK3C3GSK3BDYRK1A | |
| SCHEMBL946000 | 0.72 | PDE3B (0.43) | PDE3BPDE3APDE2APDE1APDE1B | |
| SCHEMBL23749755 | 0.72 | IGF1R (0.40) | PIK3C3GSK3BDYRK1AIGF1RTGFBR1 | |
| SCHEMBL28848830 | 0.71 | PDE3B (0.43) | PDE3BPDE3APDE2APDE1APDE1B | |
| SCHEMBL28953804 | 0.71 | PDE3B (0.40) | PDE3BPDE3APDE2APDE1APDE1B | |
| SCHEMBL1192656 | 0.70 | ATR (0.50) | GSK3BDYRK1AIGF1RTGFBR1ATR | |
| SCHEMBL828560 | 0.70 | TP53 (0.51) | — | |
| SCHEMBL30953487 | 0.70 | ATR (0.50) | GSK3BDYRK1AIGF1RTGFBR1ATR | |
| SCHEMBL23727744 | 0.69 | IGF1R (0.38) | PIK3C3GSK3BDYRK1AIGF1RTGFBR1 | |
| SCHEMBL23727741 | 0.69 | IGF1R (0.38) | PIK3C3GSK3BDYRK1AIGF1RTGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110036005-B | Amide derivatives and their use in medicine | 广东东阳光药业有限公司 | 2022-09-27 | — | — | CN | disclosed |