Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 14/20 | 0.64 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17881890 | 0.87 | RIPK1 (0.76) | RIPK1P2RX7 | |
| SCHEMBL17881976 | 0.78 | RIPK1 (1.00) | RIPK1 | |
| SCHEMBL17881984 | 0.78 | RIPK1 (1.00) | RIPK1 | |
| SCHEMBL19500984 | 0.78 | RIPK1 (0.76) | RIPK1P2RX7 | |
| SCHEMBL17881987 | 0.78 | RIPK1 (1.00) | RIPK1P2RX7 | |
| SCHEMBL17881893 | 0.78 | RIPK1 (1.00) | RIPK1P2RX7 | |
| SCHEMBL17881975 | 0.77 | RIPK1 (0.67) | RIPK1P2RX7 | |
| SCHEMBL28167616 | 0.76 | RIPK1 (0.66) | RIPK1P2RX7TACR1 | |
| SCHEMBL17881908 | 0.76 | RIPK1 (0.65) | RIPK1P2RX7 | |
| SCHEMBL17881874 | 0.76 | RIPK1 (0.65) | RIPK1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108492-A | Inhibitor of cellular necrosis | 北京生命科学研究所 | 2017-08-29 | — | — | CN | disclosed |