Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
| ▸ | RXRA | P19793 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30100625 | 1.00 | SMN1; SMN2 (0.67) | SMN1; SMN2NPC1RAB9AHPGDSMPD1 | |
| SCHEMBL4872484 | 0.95 | SMN1; SMN2 (0.76) | SMN1; SMN2NPC1RAB9AHPGDSMPD1 | |
| SCHEMBL30100607 | 0.89 | SMN1; SMN2 (0.60) | SMN1; SMN2NPC1RAB9AHPGDSMPD1 | |
| SCHEMBL30100601 | 0.88 | SMN1; SMN2 (0.63) | SMN1; SMN2NPC1RAB9AHPGDSMPD1 | |
| SCHEMBL21902756 | 0.88 | SMN1; SMN2 (0.63) | SMN1; SMN2NPC1RAB9AHPGDSMPD1 | |
| SCHEMBL12692658 | 0.88 | HPGD (0.56) | SMN1; SMN2NPC1RAB9AHPGDSMPD1 | |
| SCHEMBL20183038 | 0.87 | SMN1; SMN2 (0.64) | SMN1; SMN2NPC1RAB9AHPGDSMPD1 | |
| SCHEMBL30100610 | 0.87 | SMN1; SMN2 (0.58) | SMN1; SMN2NPC1RAB9AHPGDSMPD1 | |
| SCHEMBL6246974 | 0.85 | SMN1; SMN2 (0.78) | SMN1; SMN2NPC1RAB9AHPGDSMPD1 | |
| SCHEMBL3168608 | 0.85 | SMN1; SMN2 (0.66) | SMN1; SMN2NPC1RAB9AHPGDSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110099893-B | Preparation method of droxidopa and intermediate thereof | 广东东阳光药业有限公司 | 2022-09-27 | — | — | CN | disclosed |