Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21902756 | 1.00 | SMN1; SMN2 (0.63) | SMN1; SMN2NPC1HPGDRAB9AMEN1 | |
| SCHEMBL30951580 | 0.94 | SMN1; SMN2 (0.73) | SMN1; SMN2NPC1HPGDRAB9AMEN1 | |
| SCHEMBL3170774 | 0.94 | SMN1; SMN2 (0.73) | SMN1; SMN2NPC1HPGDRAB9AMEN1 | |
| SCHEMBL3168608 | 0.94 | SMN1; SMN2 (0.66) | SMN1; SMN2NPC1HPGDRAB9AMEN1 | |
| SCHEMBL1034120 | 0.91 | NPC1 (0.55) | SMN1; SMN2NPC1HPGDRAB9AMEN1 | |
| SCHEMBL6483625 | 0.91 | SMN1; SMN2 (0.55) | SMN1; SMN2NPC1HPGDRAB9AMEN1 | |
| SCHEMBL30100607 | 0.91 | SMN1; SMN2 (0.60) | SMN1; SMN2NPC1HPGDRAB9AMEN1 | |
| SCHEMBL3178525 | 0.89 | HPGD (0.53) | SMN1; SMN2NPC1HPGDRAB9AMEN1 | |
| SCHEMBL30100625 | 0.88 | SMN1; SMN2 (0.67) | SMN1; SMN2NPC1HPGDRAB9AMEN1 | |
| SCHEMBL28848865 | 0.88 | SMN1; SMN2 (0.67) | SMN1; SMN2NPC1HPGDRAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110099893-B | Preparation method of droxidopa and intermediate thereof | 广东东阳光药业有限公司 | 2022-09-27 | — | — | CN | disclosed |