SCHEMBL2884895

SCHEMBL2884895

Clc1cc(Cl)c2c(c1)Oc1c(Cl)c(Cl)c(Cl)c(Cl)c1O2

nearest known ligand 0.67

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
AHR P35869 15/20 0.67
ALDH1A1 P00352 3/20 0.40
TSHR P16473 2/20 0.38
HSD17B10 Q99714 2/20 0.38
HPGD P15428 1/20 0.38
FLT1 P17948 1/20 0.33
CYP3A4 P08684 2/20 0.32
RECQL P46063 1/20 0.32
CA12 O43570 1/20 0.32
CA9 Q16790 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8952151 0.89 AHR (0.82) AHRALDH1A1TSHRHSD17B10HPGD
SCHEMBL8952194 0.86 AHR (0.78) AHRALDH1A1TSHRHSD17B10FLT1
SCHEMBL9345588 0.80 AHR (1.00) AHRALDH1A1TSHRHSD17B10FLT1
SCHEMBL31696700 0.80 AHR (1.00) AHRALDH1A1TSHRHSD17B10FLT1
SCHEMBL4737802 0.80 AHR (0.69) AHRALDH1A1TSHRHSD17B10HPGD
SCHEMBL29353335 0.77 AHR (0.75) AHRALDH1A1TSHRHSD17B10HPGD
SCHEMBL2879834 0.77 AHR (0.75) AHRALDH1A1TSHRHSD17B10HPGD
SCHEMBL8952199 0.77 AHR (0.64) AHRALDH1A1TSHRHSD17B10FLT1
SCHEMBL30431628 0.77 AHR (0.70) AHRALDH1A1FLT1
SCHEMBL8958639 0.77 AHR (0.70) AHRALDH1A1FLT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7811760-B2 Vector and method for detecting the change in transcription amount KABUSHIKI KAISHA TOSHIBA (JP) 2010-10-12 US disclosed
US-20080003596-A1 VECTOR AND METHOD FOR DETECTING THE CHANGE IN TRANSCRIPTION AMOUNT KABUSHIKI KAISHA TOSHIBA (JP) 2008-01-03 US disclosed