Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 12/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.32 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8952143 | 0.94 | AHR (0.62) | AHRCYP19A1RAPGEF4ALDH1A1FLT1 | |
| SCHEMBL8952151 | 0.87 | AHR (0.82) | AHRALDH1A1FLT1CYP3A4TSHR | |
| SCHEMBL8952194 | 0.80 | AHR (0.78) | AHRALDH1A1FLT1CYP3A4TSHR | |
| SCHEMBL4737802 | 0.78 | AHR (0.69) | AHRALDH1A1FLT1CYP3A4TSHR | |
| SCHEMBL31696700 | 0.78 | AHR (1.00) | AHRALDH1A1FLT1CYP3A4TSHR | |
| SCHEMBL9345588 | 0.78 | AHR (1.00) | AHRALDH1A1FLT1CYP3A4TSHR | |
| SCHEMBL2884895 | 0.77 | AHR (0.67) | AHRALDH1A1FLT1CYP3A4TSHR | |
| SCHEMBL8958639 | 0.75 | AHR (0.70) | AHRALDH1A1FLT1 | |
| SCHEMBL30431628 | 0.75 | AHR (0.70) | AHRALDH1A1FLT1 | |
| SCHEMBL7887922 | 0.73 | AHR (0.74) | AHRFLT1CYP3A4TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990008142-A1 | SYNTHESIS AND APPLICATION OF 1,3,6,8- AND 2,4,6,8-SUBSTITUTED DIBENZOFURANS AND DIBENZO-p-DIOXINS AS ANTITUMORIGENIC AGENTS | TEXAS A&M UNIVERSITY (US) | 1990-07-26 | — | — | WO | claimed |
| US-5516790-A | Synthesis and application of alkyl-substituted dibenzofurans as antitumorigenic agents | TEXAS A&M UNIVERSITY SYSTEM TECHNOLOGY LICENSING OFFICE (US) | 1996-05-14 | — | — | US | disclosed |
| WO-1990008142-A1 | SYNTHESIS AND APPLICATION OF 1,3,6,8- AND 2,4,6,8-SUBSTITUTED DIBENZOFURANS AND DIBENZO-p-DIOXINS AS ANTITUMORIGENIC AGENTS | TEXAS A&M UNIVERSITY (US) | 1990-07-26 | — | — | WO | disclosed |