Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | QRFPR | Q96P65 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 13/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29878456 | 1.00 | HTR2A (0.38) | HTR2AHTR2CQRFPRKCNH2SIGMAR1 | |
| SCHEMBL29878230 | 0.75 | MAT2A (0.36) | QRFPRKCNH2 | |
| SCHEMBL26683570 | 0.72 | HTR2A (0.46) | HTR2AHTR2CSIGMAR1HRH4HRH3 | |
| SCHEMBL29878508 | 0.71 | HRH3 (0.42) | QRFPRKCNH2HRH3 | |
| SCHEMBL28849119 | 0.71 | HRH3 (0.42) | QRFPRKCNH2HRH3 | |
| SCHEMBL21278135 | 0.69 | HTR2A (0.73) | HTR2AHTR2CSIGMAR1 | |
| SCHEMBL17809478 | 0.69 | HTR2A (0.55) | HTR2AHTR2CSIGMAR1HRH4 | |
| SCHEMBL21671855 | 0.69 | HTR2A (0.46) | HTR2AHTR2CSIGMAR1 | |
| SCHEMBL8015265 | 0.66 | HTR2A (0.32) | HTR2AHTR2C | |
| SCHEMBL24640369 | 0.66 | HTR2A (0.33) | HTR2AHTR2CSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114940683-B | HPK1 inhibitors and uses thereof | 轩竹(北京)医药科技有限公司 | 2023-01-17 | — | — | CN | disclosed |
| CN-114940683-A | HPK1 inhibitors and uses thereof | 轩竹(北京)医药科技有限公司 | 2022-08-26 | — | — | CN | disclosed |