Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | HTT | P42858 | 4/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29950182 | 1.00 | KDM4E (0.64) | KDM4ERECQLLMNAALDH1A1HTT | |
| SCHEMBL11389635 | 0.85 | KDM4E (0.76) | KDM4ERECQLLMNAALDH1A1HTT | |
| SCHEMBL29950091 | 0.82 | KDM4E (0.62) | KDM4ERECQLLMNAALDH1A1HTT | |
| SCHEMBL28849142 | 0.82 | KDM4E (0.62) | KDM4ERECQLLMNAALDH1A1HTT | |
| SCHEMBL29950257 | 0.82 | KDM4E (0.62) | KDM4ERECQLLMNAALDH1A1HTT | |
| SCHEMBL29950469 | 0.81 | EGLN1 (0.59) | KDM4ELMNAHTTMEN1KMT2A | |
| SCHEMBL29949910 | 0.81 | KDM4E (0.64) | KDM4ERECQLLMNAALDH1A1HTT | |
| SCHEMBL28849083 | 0.81 | KDM4E (0.64) | KDM4ERECQLLMNAALDH1A1HTT | |
| SCHEMBL2383886 | 0.79 | KDM4E (1.00) | KDM4ERECQLLMNAALDH1A1HTT | |
| SCHEMBL1522936 | 0.75 | KDM4E (0.81) | KDM4ERECQLLMNAALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108069952-B | Quinolinone compound and application thereof in medicines | 广东东阳光药业有限公司 | 2022-09-27 | — | — | CN | disclosed |