Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.56 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.54 |
| ▸ | ASPH | Q12797 | 1/20 | 0.54 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29950226 | 0.83 | EGLN1 (0.64) | EGLN1HIF1ABBOX1ASPHKDM8 | |
| SCHEMBL28849034 | 0.82 | EGLN1 (0.58) | EGLN1HIF1ABBOX1ASPHKDM8 | |
| SCHEMBL29950086 | 0.82 | EGLN1 (0.58) | EGLN1HIF1ABBOX1ASPHKDM8 | |
| SCHEMBL28849092 | 0.82 | EGLN1 (0.58) | EGLN1HIF1ABBOX1ASPHKDM8 | |
| SCHEMBL8244798 | 0.82 | HIF1A (0.67) | EGLN1HIF1ABBOX1ASPHKDM8 | |
| SCHEMBL28849044 | 0.81 | KDM4E (0.64) | GSK3BKDM4EL3MBTL1HTTLMNA | |
| SCHEMBL29950182 | 0.81 | KDM4E (0.64) | GSK3BKDM4EL3MBTL1HTTLMNA | |
| SCHEMBL29949887 | 0.81 | EGLN1 (0.59) | EGLN1HIF1ABBOX1ASPHKDM8 | |
| SCHEMBL29950280 | 0.78 | EGLN1 (0.63) | EGLN1HIF1ABBOX1ASPHKDM8 | |
| SCHEMBL2382364 | 0.77 | EGLN1 (0.78) | EGLN1KDM4EL3MBTL1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108069952-B | Quinolinone compound and application thereof in medicines | 广东东阳光药业有限公司 | 2022-09-27 | — | — | CN | disclosed |