Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 3/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11252145 | 0.96 | KMT2A (0.53) | KMT2AMEN1TSHRLMNACTSK | |
| SCHEMBL28543998 | 0.96 | KMT2A (0.53) | KMT2AMEN1TSHRLMNACTSK | |
| SCHEMBL16119470 | 0.94 | MAPT (0.47) | KMT2AMEN1TSHRLMNACTSK | |
| SCHEMBL16072891 | 0.90 | KMT2A (0.49) | KMT2AMEN1TSHRLMNACTSK | |
| SCHEMBL27942852 | 0.89 | TSHR (0.51) | KMT2AMEN1TSHRLMNACTSK | |
| SCHEMBL686318 | 0.88 | TSHR (0.50) | KMT2AMEN1TSHRLMNACTSK | |
| SCHEMBL9999589 | 0.86 | TSHR (0.55) | KMT2AMEN1TSHRLMNACTSK | |
| SCHEMBL27980214 | 0.85 | TSHR (0.45) | KMT2AMEN1TSHRCTSKPOLB | |
| SCHEMBL14839354 | 0.84 | TSHR (0.47) | KMT2AMEN1TSHRLMNACTSK | |
| SCHEMBL15799989 | 0.83 | ESR1 (0.54) | KMT2AMEN1TSHRLMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107077067-A | Photosensitive polymer combination, photosensitive-resin layered product, the manufacture method of resin pattern, cured film and display device | 旭化成株式会社 | 2017-08-18 | — | — | CN | disclosed |