Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.90 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.90 |
| ▸ | LMNA | P02545 | 3/20 | 0.90 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.90 |
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Padimate O SCHEMBL1769139 | 0.95 | ALDH1A1 (1.00) | ALDH1A1CYP3A4LMNAHSD17B10TSHR | |
| Padimate O SCHEMBL29052074 | 0.95 | ALDH1A1 (1.00) | ALDH1A1CYP3A4LMNAHSD17B10TSHR | |
| Padimate O SCHEMBL15432 | 0.95 | ALDH1A1 (1.00) | ALDH1A1CYP3A4LMNAHSD17B10TSHR | |
| Padimate O SCHEMBL28272049 | 0.94 | ALDH1A1 (0.97) | ALDH1A1CYP3A4LMNAHSD17B10TSHR | |
| Padimate O SCHEMBL5246700 | 0.91 | ALDH1A1 (0.93) | ALDH1A1CYP3A4LMNAHSD17B10TSHR | |
| Padimate O SCHEMBL28250616 | 0.90 | ALDH1A1 (0.90) | ALDH1A1CYP3A4LMNAHSD17B10TSHR | |
| SCHEMBL1961174 | 0.90 | ALDH1A1 (0.90) | ALDH1A1CYP3A4LMNAHSD17B10TSHR | |
| Padimate O SCHEMBL27008006 | 0.90 | ALDH1A1 (0.84) | ALDH1A1CYP3A4LMNAHSD17B10TSHR | |
| Padimate O SCHEMBL599449 | 0.89 | ALDH1A1 (0.88) | ALDH1A1CYP3A4LMNAHSD17B10TSHR | |
| Padimate O SCHEMBL28242661 | 0.87 | ALDH1A1 (0.79) | ALDH1A1CYP3A4LMNAHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106999385-A | Oil-in-water type ultraviolet protection cosmetics | 花王株式会社 | 2017-08-01 | — | — | CN | disclosed |