Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.65 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 2/20 | 0.41 |
| ▸ | JAK3 | P52333 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21311003 | 1.00 | ALOX15 (0.65) | ALOX15PTGER4LMNACYP1A2CYP3A4 | |
| SCHEMBL2028037 | 0.90 | ALOX15 (0.80) | ALOX15PTGER4LMNACYP1A2CYP3A4 | |
| SCHEMBL2028039 | 0.90 | ALOX15 (0.80) | ALOX15PTGER4LMNACYP1A2CYP3A4 | |
| SCHEMBL21310900 | 0.89 | ALOX15 (0.82) | ALOX15PTGER4LMNACYP1A2CYP3A4 | |
| SCHEMBL13537292 | 0.87 | ALOX15 (0.64) | ALOX15PTGER4LMNACYP1A2CYP3A4 | |
| SCHEMBL3353106 | 0.86 | ALOX15 (0.63) | ALOX15PTGER4LMNACYP1A2CYP3A4 | |
| SCHEMBL15319752 | 0.85 | ALOX15 (0.88) | ALOX15PTGER4LMNACYP1A2CYP3A4 | |
| SCHEMBL20337638 | 0.82 | HDAC1 (0.52) | ALOX15CA12CA1CA2CA7 | |
| SCHEMBL22725419 | 0.81 | KMT2A (0.54) | ALOX15PTGER4LMNARAB9AMAPT | |
| SCHEMBL11621616 | 0.81 | ALOX15 (0.51) | ALOX15PTGER4LMNACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107021958-A | FXR receptor stimulating agents | 山东轩竹医药科技有限公司 | 2017-08-08 | — | — | CN | disclosed |