Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.38 |
| ▸ | NPY4R | P50391 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 2/20 | 0.37 |
| ▸ | CCND1 | P24385 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18990344 | 0.78 | NOTUM (0.59) | NOTUMTSHRRAB9AL3MBTL1HTR3E | |
| SCHEMBL9017035 | 0.78 | NOTUM (0.59) | NOTUMTSHRRAB9AL3MBTL1HTR3E | |
| SCHEMBL4467291 | 0.76 | NOTUM (0.61) | NOTUMTSHRRAB9AL3MBTL1HTR3E | |
| Trifluoroacetic Acid SCHEMBL28849397 | 0.76 | TSHR (0.57) | NOTUMTSHRRAB9AL3MBTL1HTR3E | |
| SCHEMBL18990269 | 0.75 | NOTUM (0.59) | NOTUMTSHRRAB9AL3MBTL1HTR3E | |
| SCHEMBL1173678 | 0.75 | NOTUM (0.65) | NOTUMTSHRRAB9AL3MBTL1HTR3E | |
| SCHEMBL30711215 | 0.75 | NOTUM (0.65) | NOTUMTSHRRAB9AL3MBTL1HTR3E | |
| SCHEMBL28587036 | 0.75 | NOTUM (0.47) | NOTUMTSHRRAB9AL3MBTL1HTR3E | |
| SCHEMBL691666 | 0.74 | NOTUM (0.59) | NOTUMTSHRRAB9AL3MBTL1HTR3E | |
| SCHEMBL29701136 | 0.74 | NOTUM (0.59) | NOTUMTSHRRAB9AL3MBTL1HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108512-A | Therapeutic compound and application thereof | 基因泰克公司 | 2017-08-29 | — | — | CN | disclosed |