Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 6/20 | 0.44 |
| ▸ | BUB1 | O43683 | 1/20 | 0.43 |
| ▸ | ACLY | P53396 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | HCK | P08631 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29701136 | 1.00 | NOTUM (0.59) | NOTUML3MBTL1TSHRRAB9AHTR3E | |
| SCHEMBL28085950 | 0.98 | NOTUM (0.57) | NOTUML3MBTL1TSHRRAB9AHTR3E | |
| SCHEMBL2458509 | 0.81 | ACLY (0.52) | NR1H2ACLYPIK3CDABL1EGFR | |
| SCHEMBL30711215 | 0.81 | NOTUM (0.65) | NOTUML3MBTL1TSHRRAB9AHTR3E | |
| SCHEMBL1173678 | 0.81 | NOTUM (0.65) | NOTUML3MBTL1TSHRRAB9AHTR3E | |
| SCHEMBL25010272 | 0.80 | NR1H2 (0.48) | NR1H2NR1H3 | |
| SCHEMBL26698290 | 0.80 | NOTUM (0.42) | NOTUML3MBTL1TSHRRAB9AHTR3E | |
| SCHEMBL4930238 | 0.80 | KDM4E (0.44) | NOTUML3MBTL1BCHEBUB1ACLY | |
| SCHEMBL24476978 | 0.80 | L3MBTL1 (0.51) | NOTUML3MBTL1BCHEBUB1HSP90AA1 | |
| SCHEMBL1273077 | 0.80 | HTR6 (0.49) | NOTUML3MBTL1BCHENR1H2BUB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 321 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118598851-A | 5-Aminoindole chalcone compound and preparation method and application thereof | 平顶山学院 | 2024-09-06 | — | — | CN | claimed |
| CN-103570688-B | 2,5-diaminomethyl pyrazine compounds, its pharmaceutical composition, preparation method and purposes | 中国科学院上海药物研究所 | 2016-06-08 | — | — | CN | claimed |
| CN-101535299-A | 5-lipoxygenase-activating protein (FLAP) inhibitors | AMIRA PHARMACEUTICALS INC (US) | 2009-09-16 | — | — | CN | claimed |
| US-12559455-B2 | Compound as a UBR box domain ligand | AUTOTAC INC. (KR) | 2026-02-24 | — | — | US | disclosed |
| US-20250171420-A1 | MOLECULAR GLUE DEGRADERS AND METHODS OF USING THE SAME | MONTE ROSA THERAPEUTICS AG (CH) | 2025-05-29 | — | — | US | disclosed |
| WO-2025087365-A1 | METTL3 INHIBITOR | 杭州邦顺制药有限公司 | 2025-05-01 | — | — | WO | disclosed |
| CN-119899188-A | METTL3 inhibitors | 杭州邦顺制药有限公司 | 2025-04-29 | — | — | CN | disclosed |
| CN-119816491-A | New spirocyclohexane derivatives, pharmaceutical compositions containing them and their use as anti-apoptotic inhibitors | 法国施维雅药厂 | 2025-04-11 | — | — | CN | disclosed |
| CN-119798277-A | Novel isoxazolo pyrimidine derivative with anti-novel coronavirus activity and preparation method and application thereof | 吉林大学 | 2025-04-11 | — | — | CN | disclosed |
| WO-2025067477-A1 | CYCLOPEPTIDE OF ACINETOBACTER BAUMANNII AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2025-04-03 | — | — | WO | disclosed |
| CN-119708122-A | Cyclic peptide for resisting Acinetobacter baumannii and application thereof | 武汉人福创新药物研发中心有限公司 | 2025-03-28 | — | — | CN | disclosed |
| WO-2001044235-A2 | AGENTS AND METHODS FOR THE TREATMENT OF PROLIFERATIVE DISEASES | ELI LILLY AND COMPANY (US) | 2001-06-21 | — | — | WO | disclosed |
| CN-1291892-A | Substituted oxoazaheterocyclyl factor Xa inhibitors | AWENTIS PHARMACEUTICAL INC (US) | 2001-04-18 | — | — | CN | disclosed |
| CN-1222911-A | Indolyl-pyrrolydenemethylpyrrole derivatives and process for their preparation | PHARMACIA & UPJOHN SPA (IT) | 1999-07-14 | — | — | CN | disclosed |
| EP-0909271-A1 | INDOLYL-PYRROLYDENEMETHYLPYRROLE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | PHARMACIA & UPJOHN S.p.A. (IT) | 1999-04-21 | — | — | EP | disclosed |
| US-5859007-A | TREATMENT OF DIABETES, OBESITY | GLAXO WELLCOME INC. (US) | 1999-01-12 | — | — | US | disclosed |
| WO-1998040380-A1 | INDOLYL-PYRROLYDENEMETHYLPYRROLE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | PHARMACIA & UPJOHN S.P.A. (IT) | 1998-09-17 | — | — | WO | disclosed |
| EP-0411150-B1 | INDOLE DERIVATIVES, PREPARATION THEREOF, AND DRUG FOR PREVENTING AND TREATING NEPHRITIS CONTAINING SAME | OTSUKA PHARMA CO LTD (JP) | 1996-11-27 | — | — | EP | disclosed |
| EP-0284174-B1 | THERAPEUTIC PREPARATIONS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-07-29 | — | — | EP | disclosed |
| EP-0284174-A1 | Therapeutic preparations | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-09-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12559455-B2 | Compound as a UBR box domain ligand | UBR4, UBTF, UBQLN1 | NOTUM 4607/4885L3MBTL1 1436/4885TSHR 1240/4885 |
| US-20250171420-A1 | MOLECULAR GLUE DEGRADERS AND METHODS OF USING THE SAME | PSMA1, CSNK1G1, CSNK1A1 | NOTUM 2701/4885L3MBTL1 1228/4885TSHR 4501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.