Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.92 |
| ▸ | TP53 | P04637 | 1/20 | 0.92 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.75 |
| ▸ | CA1 | P00915 | 3/20 | 0.71 |
| ▸ | CA2 | P00918 | 3/20 | 0.71 |
| ▸ | CA12 | O43570 | 1/20 | 0.71 |
| ▸ | CA3 | P07451 | 1/20 | 0.71 |
| ▸ | TYR | P14679 | 1/20 | 0.71 |
| ▸ | DRD1 | P21728 | 1/20 | 0.71 |
| ▸ | CA4 | P22748 | 1/20 | 0.71 |
| ▸ | CA6 | P23280 | 1/20 | 0.71 |
| ▸ | CA5A | P35218 | 1/20 | 0.71 |
| ▸ | CA7 | P43166 | 1/20 | 0.71 |
| ▸ | CA9 | Q16790 | 1/20 | 0.71 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.71 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.71 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.69 |
| ▸ | DAO | P14920 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL27505341 | 1.00 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL11771938 | 1.00 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL25381766 | 1.00 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL31011418 | 1.00 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL9130691 | 0.96 | TSHR (0.86) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL28895258 | 0.96 | TSHR (0.86) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL28895260 | 0.96 | TSHR (0.86) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL28582344 | 0.96 | TSHR (0.86) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL28861859 | 0.96 | TSHR (0.86) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL4450034 | 0.96 | TSHR (0.86) | TSHRTP53SRD5A2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023132630-A2 | BIODEGRADABLE THERMOPLASTIC POLYETHER ESTER ELASTOMER | 이성율 | 2023-07-13 | — | — | WO | claimed |
| CN-114105957-A | Oxitinib-terephthalic acid crystal and preparation method thereof | 鲁南制药集团股份有限公司 | 2022-03-01 | — | — | CN | claimed |
| US-10562284-B2 | Self-indicating backing paper and methods for use | THE BOEING COMPANY (US) | 2020-02-18 | — | — | US | claimed |
| CN-109592715-A | A method of using two hydration terephthalic acid (TPA) manganese as presoma controllable preparation different structure manganese oxide | 陕西师范大学 | 2019-04-09 | — | — | CN | claimed |
| CN-108271380-A | Antifouling composition | 佐敦公司 | 2018-07-10 | — | — | CN | claimed |
| CN-107913738-A | Carboxylates hybrid material of a kind of Sulfide-containing Hindered functional group and preparation method thereof | 首都师范大学 | 2018-04-17 | — | — | CN | claimed |
| WO-2017180264-A2 | SEPARATOR FOR USE IN ELECTROCHEMICAL CELLS AND METHOD OF FABRICATION THEREOF | GINER, INC. (US) | 2017-10-19 | — | — | WO | claimed |
| US-20170263908-A1 | Separator For Use in Electrochemical Cells and Method of Fabrication Thereof | GINER, INC. | 2017-09-14 | — | — | US | claimed |
| US-20150306321-A1 | METERED DOSE DISPENSING VALVE | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-10-29 | — | — | US | claimed |
| EP-2922770-A1 | METERED DOSE DISPENSING VALVE | 3M Innovative Properties Company (US) | 2015-09-30 | — | — | EP | claimed |
| WO-2014081746-A1 | METERED DOSE DISPENSING VALVE | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-05-30 | — | — | WO | claimed |
| WO-2013188609-A1 | METERED DOSE DISPENSING VALVE | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-12-19 | — | — | WO | claimed |
| EP-1468218-B1 | CO-EXTRUDED TUBING | NATVAR HOLDINGS INC (US) | 2012-06-20 | — | — | EP | claimed |
| US-7647949-B2 | Comprising outer layer of polyester, inner fluid-contact layer of polyethylene or thermoplastic polyurethane; intermediate tie layer of ethylene-vinyl acetate copolymer may be included to prevent delamination; for administration of intravenous fluids; eliminates need for inclusion of polyvinyl chloride | NATVAR HOLDINGS, INC. (US) | 2010-01-19 | — | — | US | claimed |
| US-20070119511-A1 | Co-extruded tubing | CREDIT SUISSE AG, CAYMAN ISLANDS BRANCH | 2007-05-31 | — | — | US | claimed |
| US-20040002729-A1 | Irradiation conversion of thermoplastic to thermoset polymers | ZAMORE, ALAN | 2004-01-01 | — | — | US | claimed |
| US-6596818-B1 | Radiation-crosslinkable thermoplastic polymer composition, a process for the preparation thereof, an angioplasty balloon made using such a composition, and a method of using the angioplasty balloon. | ZAMORE, ALAN | 2003-07-22 | — | — | US | claimed |
| EP-0220156-B1 | FABRIC SOFTENER COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 1990-05-30 | — | — | EP | claimed |
| US-4707506-A | Polyesterether elastomer compositions having improved flame retardant properties | OCCIDENTAL CHEMICAL CORPORATION (US) | 1987-11-17 | — | — | US | claimed |
| US-4340091-A | Elastomeric sheet materials for heart valve and other prosthetic implants | ALBANY INTERNATIONAL CORP. (US) | 1982-07-20 | — | — | US | claimed |