2-Pyrrolidone

2-Pyrrolidone

SCHEMBL28849488

CCC(=O)O.O=C1CCCN1

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OR51E2 Q9H255 1/20 0.62
CRBN Q96SW2 3/20 0.54
FKBP5 Q13451 1/20 0.54
KDM4E B2RXH2 3/20 0.43
GAA P10253 1/20 0.43
POLB P06746 1/20 0.43
FFAR3 O14843 1/20 0.42
TSHR P16473 3/20 0.34
MERTK Q12866 1/20 0.33
KMT2A Q03164 2/20 0.33
MAPT P10636 1/20 0.33
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
ITGB3 P05106 1/20 0.32
ITGB2 P05107 1/20 0.32
ITGB1 P05556 1/20 0.32
ITGAV P06756 1/20 0.32
ITGA2B P08514 1/20 0.32
ITGA5 P08648 1/20 0.32
ITGB5 P18084 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Pyrrolidone SCHEMBL27739471 0.88 OR51E2 (0.62) OR51E2CRBNFKBP5KDM4EGAA
Butyric Acid SCHEMBL27754420 0.86 OR51E2 (0.56) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL28311398 0.86 OR51E2 (0.60) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL27456228 0.85 OR51E2 (0.65) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL2155488 0.85 OR51E2 (0.71) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL5051625 0.85
2-Pyrrolidone SCHEMBL10474577 0.84
2-Pyrrolidone SCHEMBL6929736 0.84 OR51E2 (0.79) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL14977562 0.84 OR51E2 (0.79) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL14977810 0.84 OR51E2 (0.79) OR51E2CRBNFKBP5KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115845812-B Preparation method and application of magnetic lignin adsorption material 大连工业大学 2024-05-03 CN disclosed
CN-107207496-A Substituted bridged ring urea analogs as sirtuin modulators 葛兰素史密斯克莱有限责任公司 2017-09-26 CN disclosed