Propionaldehyde

Propionaldehyde

SCHEMBL28849694

Brc1occ2ccccc12.CCC=O

nearest known ligand 0.33

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 3/20 0.33
POLB P06746 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
MAPT P10636 4/20 0.32
TDP1 Q9NUW8 2/20 0.32
GAA P10253 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
ALDH1A1 P00352 2/20 0.31
MAPK1 P28482 1/20 0.31
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
GPR84 Q9NQS5 1/20 0.31
ELANE P08246 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1605255 0.83 ALDH1A1 (0.39) PTPN1POLBMEN1KMT2ATDP1
SCHEMBL28849693 0.81 ALDH1A1 (0.36) PTPN1MEN1KMT2AMAPTTDP1
Benzene SCHEMBL28263391 0.81 ALDH1A1 (0.38) POLBMEN1KMT2ATDP1CYP1A2
Naphthalene SCHEMBL9538913 0.72 ALDH1A1 (0.53) MEN1KMT2AMAPTTDP1GAA
Propionaldehyde SCHEMBL28030448 0.71 ALDH1A1 (0.41) TDP1GAAL3MBTL1CYP1A2ALDH1A1
Naphthalene SCHEMBL27832233 0.70 ALDH1A1 (0.50) MEN1KMT2AMAPTTDP1GAA
SCHEMBL1613704 0.69 PTPN1 (0.36) PTPN1POLBMEN1KMT2AMAPT
Propionaldehyde SCHEMBL27544772 0.68 ALDH1A1 (0.47) TDP1GAAL3MBTL1CYP1A2CYP2C19
Anthracene SCHEMBL27589704 0.68 ALDH1A1 (0.47) MEN1KMT2AMAPTTDP1GAA
Propionaldehyde SCHEMBL27932171 0.67 CYP2A6 (0.68) TDP1GAAL3MBTL1CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107188837-B A kind of synthetic method of α-acyl group high allyl thio-ether type compounds 温州大学 2019-05-28 CN disclosed
CN-107188837-A A kind of synthetic method of α acyl groups high allyl thio-ether type compounds 温州大学 2017-09-22 CN disclosed