Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.47 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16708752 | 0.86 | ALDH1A1 (0.59) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL25524547 | 0.85 | ALDH1A1 (0.55) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL30998124 | 0.85 | MAPT (0.68) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL3233829 | 0.85 | MAPT (0.68) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL3691554 | 0.84 | ALDH1A1 (0.57) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL10962265 | 0.82 | MAPT (0.69) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL11994258 | 0.82 | MAPT (0.58) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL12748075 | 0.81 | KDM4E (0.50) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL25341613 | 0.80 | MAPT (0.70) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL274964 | 0.80 | KDM4E (0.70) | ALDH1A1KDM4EMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115109028-A | Oxime ester compound and preparation method and application thereof | 安庆师范大学 | 2022-09-27 | — | — | CN | claimed |