SCHEMBL28850339

SCHEMBL28850339

Oc1ccc(-c2ccc(N(Cc3ccccc3)c3ccccc3)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.58
ESR2 Q92731 3/20 0.58
MMP3 P08254 1/20 0.50
BCL2L1 Q07817 1/20 0.50
LTB4R2 Q9NPC1 1/20 0.48
MEN1 O00255 2/20 0.47
MAPT P10636 2/20 0.47
KMT2A Q03164 2/20 0.47
NR3C2 P08235 1/20 0.47
ALDH1A1 P00352 1/20 0.47
HSP90AA1 P07900 1/20 0.47
GAA P10253 1/20 0.47
HDAC1 Q13547 1/20 0.46
HDAC8 Q9BY41 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
CYP19A1 P11511 1/20 0.45
G6PC1 P35575 1/20 0.44
PDK1 Q15118 1/20 0.42
PTPN1 P18031 1/20 0.42
KCNA3 P22001 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11514262 0.94 ESR1 (0.63) ESR1ESR2MEN1MAPTKMT2A
SCHEMBL1702260 0.90 NR3C2 (0.54) ESR1ESR2NR3C2ALDH1A1HDAC1
SCHEMBL11874481 0.88 ESR1 (0.66) ESR1ESR2LTB4R2MEN1MAPT
SCHEMBL66561 0.86 TAAR1 (0.54) ESR1ESR2NR3C2ALDH1A1HDAC1
SCHEMBL14373647 0.86 TAAR1 (0.54) ESR1ESR2NR3C2ALDH1A1HDAC1
Sulfuric Acid SCHEMBL6029608 0.86 ESR1 (0.58) ESR1ESR2MEN1MAPTKMT2A
SCHEMBL23435088 0.85 NR3C2 (0.50) ESR1ESR2MEN1MAPTKMT2A
SCHEMBL25823394 0.85 NR3C2 (0.50) ESR1ESR2MEN1MAPTKMT2A
SCHEMBL23992546 0.84 TAAR1 (0.57) ESR1ESR2MEN1KMT2ANR3C2
SCHEMBL9215743 0.84 TAAR1 (0.56) ESR1ESR2LTB4R2NR3C2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110167910-B Synthesis of benzyl anilino phenyl phenol ligand 尤尼威蒂恩技术有限责任公司 2022-10-04 CN disclosed
CN-110167910-B Synthesis of benzyl anilino phenyl phenol ligand 尤尼威蒂恩技术有限责任公司 2022-10-04 CN disclosed