SCHEMBL2885036

SCHEMBL2885036

CNc1ccccc1C(=O)c1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.66
KDM4E B2RXH2 1/20 0.60
POLB P06746 1/20 0.60
ATM Q13315 1/20 0.60
ALDH1A1 P00352 5/20 0.59
AKR1C3 P42330 2/20 0.57
MAPT P10636 2/20 0.55
TSHR P16473 1/20 0.55
GAA P10253 1/20 0.53
BDKRB1 P46663 3/20 0.50
NPC1 O15118 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
RAB9A P51151 1/20 0.49
NPSR1 Q6W5P4 1/20 0.47
MEN1 O00255 2/20 0.47
USP2 O75604 1/20 0.47
LMNA P02545 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31541257 1.00 KMT2A (0.66) KMT2AKDM4EPOLBATMALDH1A1
SCHEMBL4326736 0.94 ATM (0.62) KMT2AKDM4EPOLBATMALDH1A1
SCHEMBL28160181 0.91 KMT2A (0.57) KMT2AKDM4EPOLBATMALDH1A1
SCHEMBL28325053 0.89 KMT2A (0.55) KMT2AKDM4EPOLBATMALDH1A1
SCHEMBL8628627 0.89 POLB (0.67) KMT2AKDM4EPOLBATMALDH1A1
SCHEMBL31541293 0.89 ATM (0.62) KMT2AKDM4EPOLBATMALDH1A1
SCHEMBL8426419 0.86 KMT2A (0.57) KMT2AKDM4EPOLBATMALDH1A1
SCHEMBL8174226 0.85 KMT2A (0.62) KMT2AKDM4EATMALDH1A1AKR1C3
SCHEMBL27955677 0.85 KMT2A (0.54) KMT2AKDM4EPOLBATMALDH1A1
SCHEMBL31541220 0.85 AKR1C3 (0.61) KMT2AKDM4EPOLBATMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114044870-B Polyurethane chain extender and preparation method thereof, and cast polyurethane elastomer and preparation method thereof 万华化学集团股份有限公司 2023-05-26 CN claimed
CN-112723342-B Phosphorus-containing functionalized graphene and preparation method and application thereof 中国石油化工股份有限公司 2023-02-24 CN claimed
CN-114044870-A Polyurethane chain extender and preparation method thereof, and casting polyurethane elastomer and preparation method thereof 万华化学集团股份有限公司 2022-02-15 CN claimed
CN-112723342-A Phosphorus-containing functionalized graphene and preparation method and application thereof 中国石油化工股份有限公司 2021-04-30 CN claimed
CN-108912047-A The synthetic method of acridone derivatives 广州中医药大学(广州中医药研究院) 2018-11-30 CN claimed
CN-108503794-A One kind having diffusing reflection high transmittance polyurethane film and preparation method thereof 上海伟星光学有限公司 2018-09-07 CN claimed
CN-107092043-A 1.67 polyurethane eyeglasses and its manufacture method with protection royal purple optical property 上海伟星光学有限公司 2017-08-25 CN claimed
CN-106883450-A A kind of rich phosphatization Graphene fire retardant and preparation method thereof 无锡市惠山区川大石墨烯应用研究中心 2017-06-23 CN claimed
CN-103012722-A Photocuring polyurethane resin for leather or synthetic leather coating decoration and preparation method for photocuring polyurethane resin HEBEI ZHISHENG ENVIRONMENTAL PROT TECHNOLOGY CO LTD 2013-04-03 CN claimed
US-20230201787-A1 SYSTEMS AND METHODS FOR SYNTHESIZING CHEMICAL PRODUCTS, INCLUDING ACTIVE PHARMACEUTICAL INGREDIENTS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-06-29 US disclosed
CN-114044870-B Polyurethane chain extender and preparation method thereof, and cast polyurethane elastomer and preparation method thereof 万华化学集团股份有限公司 2023-05-26 CN disclosed
CN-111324008-B Photosensitive composition and application thereof 乐凯华光印刷科技有限公司 2023-04-14 CN disclosed
CN-112723342-B Phosphorus-containing functionalized graphene and preparation method and application thereof 中国石油化工股份有限公司 2023-02-24 CN disclosed
CN-107033077-B Compound, colorant composition comprising the same, and resin composition comprising the same 株式会社易美太 2022-05-24 CN disclosed
US-4062823-A PAINTS FORD MOTOR COMPANY (US) 1977-12-13 US disclosed
US-4052280-A PHOTOSENTIZER IN BACKBONE OF POLYMER SCM CORPORATION (US) 1977-10-04 US disclosed
US-4051308-A Process for polymerizing butadiene with cobalt complex, AlR3 and CS2 THE FIRESTONE TIRE & RUBBER COMPANY (US) 1977-09-27 US disclosed
US-4039414-A ACRYLYL, ACRYLAMIDE, OR ALLYL POLYMERS, BENZALDEHYDE SENSITIZER SCM CORPORATION (US) 1977-08-02 US disclosed
US-4017313-A Photosensitive composition containing a leuco dye, a photosensitizer, an aromatic aldehyde and a secondary or tertiary amine and the use thereof in a direct-print process E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-04-12 US disclosed
US-3993856-A CATALYST OF COBALT COMPOUND, HYDRO- OR HYDROCARBYLALUMINUM DIHALIDE, AND CARBON DISULFIDE THE FIRESTONE TIRE & RUBBER COMPANY (US) 1976-11-23 US disclosed