SCHEMBL28850772

SCHEMBL28850772

O=C(NN(C(=O)CC(=O)N(NC(=O)c1ccccc1)C(=O)c1ccccc1)C(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
POLB P06746 1/20 0.53
GAA P10253 1/20 0.47
HDAC1 Q13547 4/20 0.45
HDAC6 Q9UBN7 4/20 0.45
HDAC3 O15379 2/20 0.45
HDAC7 Q8WUI4 2/20 0.45
HDAC8 Q9BY41 2/20 0.45
ALOX15 P16050 2/20 0.45
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
IDO1 P14902 1/20 0.45
CA9 Q16790 1/20 0.45
HDAC2 Q92769 1/20 0.45
HSD17B10 Q99714 1/20 0.45
NCOR2 Q9Y618 1/20 0.45
CYP3A4 P08684 2/20 0.45
HDAC10 Q969S8 1/20 0.45
CYP2C9 P11712 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11861692 0.93 TDP1 (0.53) TDP1L3MBTL1POLBGAAHDAC1
SCHEMBL265617 0.88 TDP1 (0.63) TDP1L3MBTL1POLBGAAHDAC1
SCHEMBL28460956 0.88 L3MBTL1 (0.51) TDP1L3MBTL1POLBGAAHDAC1
SCHEMBL11857311 0.86 TDP1 (0.50) TDP1L3MBTL1POLBGAAHDAC1
SCHEMBL28551253 0.86 L3MBTL1 (0.50) TDP1L3MBTL1POLBGAAHDAC1
SCHEMBL28981637 0.86 L3MBTL1 (0.50) TDP1L3MBTL1POLBGAAHDAC1
Ethylene Glycol SCHEMBL28193873 0.85 TDP1 (0.56) TDP1L3MBTL1POLBGAAHDAC1
SCHEMBL11859925 0.84 TDP1 (0.47) TDP1L3MBTL1POLBGAAHDAC1
SCHEMBL29123218 0.84 L3MBTL1 (0.47) TDP1L3MBTL1POLBGAAHDAC1
Benzene SCHEMBL28121114 0.83 POLB (0.59) TDP1L3MBTL1POLBHDAC1HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113337090-B Heat-resistant modified polylactic acid material and preparation method and application thereof 湖南航天磁电有限责任公司 2023-04-18 CN claimed
CN-112940264-B Modified polylactic acid material, preparation method and application thereof 苏州市和好塑业有限公司 2022-09-27 CN claimed
CN-113337090-B Heat-resistant modified polylactic acid material and preparation method and application thereof 湖南航天磁电有限责任公司 2023-04-18 CN disclosed