Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 1/20 | 0.70 |
| ▸ | FOLH1 | Q04609 | 8/20 | 0.56 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.56 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.56 |
| ▸ | BMP1 | P13497 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GGH | Q92820 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isospaglumic Acid SCHEMBL27542882 | 1.00 | GNPAT (0.70) | GNPATFOLH1NAALAD2RIMKLABMP1 | |
| Isospaglumic Acid SCHEMBL288514 | 1.00 | GNPAT (0.70) | GNPATFOLH1NAALAD2RIMKLABMP1 | |
| SCHEMBL31194414 | 1.00 | GNPAT (0.70) | GNPATFOLH1NAALAD2RIMKLABMP1 | |
| Isospaglumic Acid SCHEMBL31121839 | 1.00 | GNPAT (0.70) | GNPATFOLH1NAALAD2RIMKLABMP1 | |
| Isospaglumic Acid SCHEMBL6438535 | 0.98 | GNPAT (0.68) | GNPATFOLH1NAALAD2RIMKLABMP1 | |
| SCHEMBL29517621 | 0.94 | GNPAT (0.63) | GNPATFOLH1NAALAD2RIMKLABMP1 | |
| SCHEMBL13467302 | 0.93 | GNPAT (0.60) | GNPATFOLH1NAALAD2RIMKLABMP1 | |
| SCHEMBL17950968 | 0.93 | GNPAT (0.60) | GNPATFOLH1NAALAD2RIMKLABMP1 | |
| SCHEMBL19106177 | 0.93 | GNPAT (0.60) | GNPATFOLH1NAALAD2RIMKLABMP1 | |
| SCHEMBL2248714 | 0.93 | GNPAT (0.60) | GNPATFOLH1NAALAD2RIMKLABMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 346 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114965800-B | Renal clear cell carcinoma biomarker and application thereof in early screening | 山西医科大学 | 2024-02-20 | — | — | CN | claimed |
| US-20240033124-A1 | DRUG DELIVERY CONTACT LENS AND OPHTHALMIC PHARMACEUTICAL COMPOSITION | DAE WON PHARMACEUTICAL CO., LTD (KR) | 2024-02-01 | — | — | US | claimed |
| EP-4275675-A1 | DRUG DELIVERY CONTACT LENS AND OPHTHALMIC PHARMACEUTICAL COMPOSITION | Dae Won Pharmaceutical Co., Ltd. (KR) | 2023-11-15 | — | — | EP | claimed |
| CN-113960200-B | Use of metabolic markers for diagnosing ADHD combined tic disorders in children | 首都医科大学附属北京儿童医院 | 2023-06-20 | — | — | CN | claimed |
| CN-114965800-A | Renal clear cell carcinoma biomarker and application thereof in early screening | 山西医科大学 | 2022-08-30 | — | — | CN | claimed |
| US-20210388080-A1 | TARGETING CONSTRUCTS BASED ON NATURAL ANTIBODIES AND USES THEREOF | DEPARTMENT OF VETERANS AFFAIRS (US) | 2021-12-16 | — | — | US | claimed |
| EP-3546940-B1 | BIOMARKERS RELATED TO KIDNEY FUNCTION AND METHODS USING THE SAME | METABOLON INC (US) | 2021-02-17 | — | — | EP | claimed |
| EP-3546940-A1 | BIOMARKERS RELATED TO KIDNEY FUNCTION AND METHODS USING THE SAME | Metabolon, Inc. (US) | 2019-10-02 | — | — | EP | claimed |
| EP-2564194-B1 | METABOLIC BIOMARKERS OF AUTISM | WISCONSIN ALUMNI RES FOUND (US) | 2019-07-10 | — | — | EP | claimed |
| US-10330688-B2 | Metabolic biomarkers of autism | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2019-06-25 | — | — | US | claimed |
| US-20120190055-A1 | MOLECULE BIOMARKERS OF AUTISM | STEMINA BIOMARKER DISCOVERY, INC. (US) | 2012-07-26 | — | — | US | claimed |
| WO-2011139914-A1 | METABOLIC BIOMARKERS OF AUTISM | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2011-11-10 | — | — | WO | claimed |
| WO-2011044253-A1 | METABOLIC BIOMARKERS OF DRUG-INDUCED CARDIOTOXICITY | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2011-04-14 | — | — | WO | claimed |
| US-20110081675-A1 | Metabolic Biomarkers Of Drug-Induced Cardiotoxicity | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2011-04-07 | — | — | US | claimed |
| US-20100116691-A1 | BIOSENSOR FOR CONTINUOUS MONITORING OF METABOLITES AND PROTEINS AND METHODS OF MANUFACTURE THEREOF | UNIVERSITY OF CONNECTICUT (US) | 2010-05-13 | — | — | US | claimed |
| US-20100104645-A1 | METHODS FOR THE PREPARATION OF TARGETING AGENT FUNCTIONALIZED DIBLOCK COPOLYMERS FOR USE IN FABRICATION OF THERAPEUTIC TARGETED NANOPARTICLES | BIND BIOSCIENCES, INC. (US) | 2010-04-29 | — | — | US | claimed |
| US-20100087337-A1 | High Throughput Fabrication of Nanoparticles | BIND BIOSCIENCES, INC. (US) | 2010-04-08 | — | — | US | claimed |
| WO-2010030763-A2 | HIGH THROUGHPUT FABRICATION OF NANOPARTICLES | BIND BIOSCIENCES, INC. (US) | 2010-03-18 | — | — | WO | claimed |
| US-7399461-B2 | Prostate-specific membrane antigen and uses thereof | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2008-07-15 | — | — | US | claimed |
| EP-1754788-A2 | Prostate-specific membrane antigen and uses thereof | Sloan-Kettering Institute For Cancer Research (US) | 2007-02-21 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100104645-A1 | METHODS FOR THE PREPARATION OF TARGETING AGENT FUNCTIONALIZED DIBLOCK COPOLYMERS FOR USE IN FABRICATION OF THERAPEUTIC TARGETED NANOPARTICLES | GNE, EPHA2, PAM | GNPAT 1063/4885FOLH1 1373/4885NAALAD2 1214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.