Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 3/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1168220 | 0.81 | IDO1 (0.52) | CYP3A4TSHRRECQLIDO1MEN1 | |
| SCHEMBL18415207 | 0.79 | SMN1; SMN2 (0.46) | CYP3A4TSHRRECQLIDO1MEN1 | |
| Methoxymethane SCHEMBL11831198 | 0.77 | CYP3A4 (0.61) | CYP3A4TSHRRECQLIDO1MEN1 | |
| SCHEMBL9191849 | 0.75 | MAPK1 (0.55) | ALDH1A1KDM4ELMNANPC1RAB9A | |
| SCHEMBL28851826 | 0.75 | IDO1 (0.49) | CYP3A4TSHRRECQLIDO1MEN1 | |
| SCHEMBL8926002 | 0.75 | ANPEP (0.47) | CNR1CNR2ESR2KDM6BKDM6A | |
| SCHEMBL4636219 | 0.75 | ESR2 (0.55) | CYP3A4RECQLMEN1KMT2AMAPT | |
| SCHEMBL28278780 | 0.74 | CYP3A4 (0.62) | CYP3A4TSHRRECQLIDO1MEN1 | |
| SCHEMBL1368372 | 0.73 | IDO1 (0.59) | CYP3A4TSHRRECQLIDO1MEN1 | |
| SCHEMBL1163819 | 0.72 | HPGD (0.49) | CYP3A4TSHRMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114957357-A | Aminoglycoside derivatives and their use in the treatment of genetic disorders | ELOXX制药有限公司 | 2022-08-30 | — | — | CN | disclosed |