Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.54 |
| ▸ | TYR | P14679 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.50 |
| ▸ | EP300 | Q09472 | 1/20 | 0.49 |
| ▸ | PTPRC | P08575 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TDP2 | O95551 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7794270 | 0.82 | GAA (0.53) | MAPK1TYRHTTEP300ALDH1A1 | |
| SCHEMBL5536448 | 0.78 | MAPK1 (0.69) | MAPK1PARP14HTTEP300ALDH1A1 | |
| SCHEMBL29721986 | 0.78 | MAPK1 (0.69) | MAPK1PARP14HTTEP300ALDH1A1 | |
| SCHEMBL26646514 | 0.77 | SOAT1 (0.78) | MAPK1PARP14HTTSOAT1ALDH1A1 | |
| SCHEMBL28457710 | 0.75 | TRPV1 (0.53) | MAPK1TYRHTTALDH1A1HCAR2 | |
| SCHEMBL11722439 | 0.75 | TRPV1 (0.67) | RAB9AKDM4E | |
| SCHEMBL28851825 | 0.75 | CYP3A4 (0.51) | HTTALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL23417745 | 0.73 | POLB (0.51) | MAPK1TYRHTTEP300ALDH1A1 | |
| SCHEMBL9156446 | 0.73 | GAA (0.57) | EP300ALDH1A1KDM4E | |
| SCHEMBL20714016 | 0.73 | HTT (0.61) | MAPK1HTTALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4889853-A | CEREBRAL INSUFFICIENCY; NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS; ANTIHYPOXIA AGENTS | SUNTORY LIMITED (JP) | 1989-12-26 | — | — | US | claimed |
| EP-0298758-A2 | Hydroquinonylphenyl butyric acid amide derivative | SUNTORY LIMITED (JP) | 1989-01-11 | — | — | EP | claimed |
| EP-0298758-B1 | Hydroquinonylphenyl butyric acid amide derivative | SUNTORY LTD (JP) | 1995-06-28 | — | — | EP | disclosed |
| EP-0298758-B1 | Hydroquinonylphenyl butyric acid amide derivative | SUNTORY LTD (JP) | 1995-06-28 | — | — | EP | disclosed |
| US-4889853-A | CEREBRAL INSUFFICIENCY; NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS; ANTIHYPOXIA AGENTS | SUNTORY LIMITED (JP) | 1989-12-26 | — | — | US | disclosed |
| US-4889853-A | CEREBRAL INSUFFICIENCY; NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS; ANTIHYPOXIA AGENTS | SUNTORY LIMITED (JP) | 1989-12-26 | — | — | US | disclosed |
| EP-0298758-A2 | Hydroquinonylphenyl butyric acid amide derivative | SUNTORY LIMITED (JP) | 1989-01-11 | — | — | EP | disclosed |
| EP-0298758-A2 | Hydroquinonylphenyl butyric acid amide derivative | SUNTORY LIMITED (JP) | 1989-01-11 | — | — | EP | disclosed |
| EP-0298758-A2 | Hydroquinonylphenyl butyric acid amide derivative | SUNTORY LIMITED (JP) | 1989-01-11 | — | — | EP | disclosed |