SCHEMBL28851971

SCHEMBL28851971

C1=Cc2cc3ccccc3cc2SN1

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
MAPK1 P28482 1/20 0.36
RAB9A P51151 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
NOX1 Q9Y5S8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8274 0.74 PARP1 (0.34) GAAMAPTNOX1
SCHEMBL5686105 0.74 PARP1 (0.34) GAAMAPTNOX1
Ammonia Solution, Strong SCHEMBL10515014 0.72 PARP1 (0.33) GAAMAPTNOX1
Fluoride SCHEMBL27762528 0.72 PARP1 (0.33) GAAMAPTNOX1
SCHEMBL38654629 0.72 PARP1 (0.33) GAAMAPTNOX1
Hydrochloric Acid SCHEMBL6424271 0.72 PARP1 (0.38) GAAMAPTNOX1
Fluoride SCHEMBL28896860 0.71 PARP1 (0.32) GAAMAPT
Hydrochloric Acid SCHEMBL8939837 0.71 PARP1 (0.36) GAAMAPT
Formaldehyde SCHEMBL28424513 0.69 PARP1 (0.31)
SCHEMBL27841860 0.69 CYP1A2 (0.39) MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114988995-A Method for continuously producing methacrolein by condensing formaldehyde and propionaldehyde 上海师范大学 2022-09-02 CN disclosed