Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.71 |
| ▸ | HPGD | P15428 | 4/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31396762 | 1.00 | POLB (0.71) | POLBHPGDMAPTNPC1TSHR | |
| SCHEMBL14520778 | 0.88 | ALDH1A1 (0.63) | POLBHPGDMAPTNPC1TSHR | |
| SCHEMBL13212973 | 0.84 | TDP1 (0.73) | POLBHPGDMAPTNPC1TSHR | |
| SCHEMBL12756960 | 0.83 | POLB (1.00) | POLBHPGDMAPTNPC1TSHR | |
| SCHEMBL5524723 | 0.83 | HPGD (0.67) | POLBHPGDMAPTNPC1TSHR | |
| SCHEMBL29818022 | 0.83 | POLB (0.71) | POLBHPGDMAPTNPC1TSHR | |
| SCHEMBL1490952 | 0.82 | HPGD (0.76) | POLBHPGDMAPTNPC1TSHR | |
| SCHEMBL14117292 | 0.81 | POLB (0.71) | POLBHPGDMAPTNPC1TSHR | |
| SCHEMBL1291842 | 0.81 | HPGD (0.71) | POLBHPGDMAPTNPC1TSHR | |
| SCHEMBL14093040 | 0.80 | POLB (0.77) | POLBHPGDMAPTNPC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107226785-B | Adamantane styrenic derivatives and its preparation method and application | 长春工业大学 | 2019-08-30 | — | — | CN | disclosed |
| CN-107226785-A | Adamantane styrenic derivatives and its preparation method and application | 长春工业大学 | 2017-10-03 | — | — | CN | disclosed |