Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ESRRA | P11474 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | PNLIP | P16233 | 2/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2885198 | 1.00 | HTR2A (0.43) | HTR2ASLC6A4L3MBTL1TDP1PTGDR2 | |
| SCHEMBL2885202 | 1.00 | HTR2A (0.43) | HTR2ASLC6A4L3MBTL1TDP1PTGDR2 | |
| SCHEMBL2894407 | 1.00 | HTR2A (0.43) | HTR2ASLC6A4L3MBTL1TDP1PTGDR2 | |
| SCHEMBL13028234 | 0.84 | HTR2A (0.52) | HTR2ASLC6A4L3MBTL1TDP1PTGDR2 | |
| SCHEMBL2890300 | 0.84 | HTR2A (0.52) | HTR2ASLC6A4L3MBTL1TDP1PTGDR2 | |
| SCHEMBL16316797 | 0.81 | L3MBTL1 (0.56) | L3MBTL1TDP1PTGDR2MEN1KMT2A | |
| SCHEMBL13028228 | 0.80 | L3MBTL1 (0.41) | HTR2ASLC6A4L3MBTL1TDP1PTGDR2 | |
| SCHEMBL13028232 | 0.80 | L3MBTL1 (0.41) | HTR2ASLC6A4L3MBTL1TDP1PTGDR2 | |
| SCHEMBL13028229 | 0.80 | L3MBTL1 (0.41) | HTR2ASLC6A4L3MBTL1TDP1PTGDR2 | |
| SCHEMBL13028233 | 0.80 | L3MBTL1 (0.43) | HTR2ASLC6A4L3MBTL1TDP1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8558028-B2 | Compound capable of inhibiting 17-beta hydroxysteriod dehydrogenase | UNIVERSITY OF BATH OF CLAVERTON DOWN (GB) | 2013-10-15 | — | — | US | disclosed |
| US-20100286204-A1 | COMPOUND CAPABLE OF INHIBITING 17-BETA HYDROXYSTERIOD DEHYDROGENASE | STERIX LIMITED (GB) | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286204-A1 | COMPOUND CAPABLE OF INHIBITING 17-BETA HYDROXYSTERIOD DEHYDROGENASE | HSD17B13, HSD17B3, HSD3B2 | HTR2A 1938/4885SLC6A4 1489/4885L3MBTL1 2881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.