Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.34 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | TYR | P14679 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28851737 | 0.85 | CACNA2D1 (0.34) | CACNA2D1CACNB2CACNA1CTAAR1HCAR2 | |
| SCHEMBL15161789 | 0.71 | — | — | |
| SCHEMBL19973268 | 0.69 | ALDH1A1 (0.40) | TAAR1ADRA2AADRA2CCYP2D6LMNA | |
| SCHEMBL19926962 | 0.68 | — | — | |
| SCHEMBL28175601 | 0.68 | — | — | |
| SCHEMBL25948555 | 0.68 | HCAR2 (0.38) | TAAR1HCAR2ADRA2AADRA2CCYP2D6 | |
| SCHEMBL15302056 | 0.66 | HCAR2 (0.41) | TAAR1HCAR2ADRA2AADRA2CCYP2D6 | |
| SCHEMBL19926958 | 0.65 | CACNA2D1 (0.30) | CACNA2D1CACNB2CACNA1C | |
| SCHEMBL21112738 | 0.65 | CACNA2D1 (0.30) | CACNA2D1CACNB2CACNA1C | |
| SCHEMBL6420857 | 0.65 | TAAR1 (0.42) | TAAR1ADRA2AADRA2CCYP2D6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107226822-A | A kind of preparation method of hexa-atomic silaoxacyclen | 杭州师范大学 | 2017-10-03 | — | — | CN | disclosed |