Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | MARK3 | P27448 | 1/20 | 0.48 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.48 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.48 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.48 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | SPR | P35270 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29595692 | 0.82 | PIM1 (0.50) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL22911971 | 0.82 | PIM1 (0.50) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL24900428 | 0.77 | PIM1 (0.42) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL30523903 | 0.76 | PARP1 (0.45) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL30523904 | 0.76 | PARP1 (0.45) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL31424128 | 0.76 | PIM1 (0.48) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL28553930 | 0.75 | DYRK1A (0.48) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL30076963 | 0.75 | PIM1 (0.49) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL29236564 | 0.73 | L3MBTL1 (0.57) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL28852671 | 0.73 | PIM1 (0.46) | PIM1MARK3MAP4K2CAMK2BPIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114133394-B | Compound selectively aiming at activity of cell cycle dependent kinase 12, preparation method and medical application | 赛诺哈勃药业（成都）有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-114133394-A | Compound selectively aiming at activity of cell cycle dependent kinase 12, preparation method and medical application | 赛诺哈勃药业（成都）有限公司 | 2022-03-04 | — | — | CN | disclosed |