SCHEMBL28852963

SCHEMBL28852963

Cc1cccc(CN2CCOCC2)c1C

nearest known ligand 0.75

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP2A13 Q16696 6/20 0.75
CYP2C9 P11712 1/20 0.51
ALOX15 P16050 1/20 0.51
HSD17B10 Q99714 1/20 0.51
KMT2A Q03164 3/20 0.51
ATM Q13315 1/20 0.51
CXCR4 P61073 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.49
ALDH1A1 P00352 2/20 0.49
KDM4E B2RXH2 1/20 0.49
MEN1 O00255 1/20 0.47
LMNA P02545 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4108854 0.86 CYP2A13 (1.00) CYP2A13CYP2C9ALOX15HSD17B10KMT2A
Hydrochloric Acid SCHEMBL11239603 0.84 CYP2A13 (0.96) CYP2A13CYP2C9ALOX15HSD17B10KMT2A
SCHEMBL21400926 0.84 KMT2A (0.53) CYP2A13KMT2AALDH1A1KDM4EMEN1
SCHEMBL3722909 0.83 CYP2A13 (0.61) CYP2A13CYP2C9ALOX15HSD17B10KMT2A
SCHEMBL28972223 0.83 CYP2A13 (0.71) CYP2A13CYP2C9ALOX15HSD17B10KMT2A
SCHEMBL13849993 0.83 CYP2A13 (0.71) CYP2A13CYP2C9ALOX15HSD17B10KMT2A
SCHEMBL9060001 0.83 CYP2A13 (0.71) CYP2A13CYP2C9ALOX15HSD17B10KMT2A
SCHEMBL17724132 0.83 CYP2A13 (0.71) CYP2A13CYP2C9ALOX15HSD17B10KMT2A
SCHEMBL13293671 0.82 ALDH1A1 (0.54) CYP2A13KMT2AALDH1A1KDM4EMEN1
SCHEMBL19532829 0.81 CYP2A13 (0.67) CYP2A13CYP2C9ALOX15HSD17B10KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107567449-A Tricyclic piperidine compounds 埃科特莱茵药品有限公司 2018-01-09 CN disclosed