Toluene

Toluene

SCHEMBL28853002

Cc1ccccc1.ClN(Cl)c1ccccc1

nearest known ligand 0.58

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.58
TSHR P16473 2/20 0.58
LMNA P02545 2/20 0.58
ALOX12 P18054 1/20 0.58
CA12 O43570 2/20 0.41
CA9 Q16790 2/20 0.41
CYP2C19 P33261 1/20 0.40
HTT P42858 2/20 0.37
HPGD P15428 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
TRPM8 Q7Z2W7 2/20 0.36
ALDH1A1 P00352 3/20 0.36
NPC1 O15118 1/20 0.35
JAK2 O60674 1/20 0.35
RAB9A P51151 1/20 0.35
PAX8 Q06710 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18812 0.86
SCHEMBL28381795 0.83 ALDH1A1 (0.39) TSHRALOX12CA12CA9CYP2C19
Hydrochloric Acid SCHEMBL8530750 0.83 ALDH1A1 (0.39) TSHRALOX12CA12CA9CYP2C19
SCHEMBL2146469 0.80 ALDH1A1 (0.55) ACHETSHRLMNAALOX12CA9
Nitrogen SCHEMBL4342761 0.80 ALDH1A1 (0.38) TSHRALOX12CA12CA9CYP2C19
Toluene SCHEMBL30089007 0.80
Toluene SCHEMBL14537407 0.78 TSHR (0.65) ACHETSHRLMNAALOX12CA12
Toluene SCHEMBL28564934 0.78 TSHR (0.65) ACHETSHRLMNAALOX12CA12
Toluene SCHEMBL5141031 0.76
Toluene SCHEMBL10989418 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107235860-A A kind of synthesis technique of the dichlorophenyl isocyanate of diuron intermediate 3,4 安徽广信农化股份有限公司 2017-10-10 CN disclosed