Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL58249 | 1.00 | KMT2A (0.34) | KMT2AMEN1PRMT5WDR77CRHBP | |
| SCHEMBL28853081 | 1.00 | KMT2A (0.34) | KMT2AMEN1PRMT5WDR77CRHBP | |
| SCHEMBL1694151 | 0.82 | KMT2A (0.41) | KMT2AMEN1PRMT5WDR77ALDH1A1 | |
| SCHEMBL981024 | 0.82 | KMT2A (0.41) | KMT2AMEN1PRMT5WDR77ALDH1A1 | |
| SCHEMBL981027 | 0.82 | KMT2A (0.41) | KMT2AMEN1PRMT5WDR77ALDH1A1 | |
| SCHEMBL336604 | 0.82 | KMT2A (0.41) | KMT2AMEN1PRMT5WDR77ALDH1A1 | |
| SCHEMBL1720326 | 0.82 | KMT2A (0.41) | KMT2AMEN1PRMT5WDR77ALDH1A1 | |
| SCHEMBL1787921 | 0.82 | KMT2A (0.41) | KMT2AMEN1PRMT5WDR77ALDH1A1 | |
| SCHEMBL58850 | 0.80 | MEN1 (0.34) | KMT2AMEN1PRMT5WDR77ALDH1A1 | |
| SCHEMBL3899549 | 0.78 | TSHR (0.48) | KMT2AMEN1ALDH1A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107406386-A | Method for producing 1 (4 hydroxy phenyl) 4 (4 trifluoromethoxy phenoxy group) piperidines or its salt | 大塚制药株式会社 | 2017-11-28 | — | — | CN | disclosed |