Benzofuran

Benzofuran

SCHEMBL28853181

O=Cc1ccccc1.c1ccc2occc2c1

nearest known ligand 0.56

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.56
ALDH1A1 P00352 3/20 0.54
MAOB P27338 3/20 0.38
MAOA P21397 1/20 0.38
FTO Q9C0B1 1/20 0.38
KMT2A Q03164 2/20 0.38
RAB9A P51151 2/20 0.38
MEN1 O00255 1/20 0.38
CTNNB1 P35222 1/20 0.38
WNT3A P56704 1/20 0.38
CA12 O43570 2/20 0.35
CA2 P00918 2/20 0.35
CA1 P00915 1/20 0.35
LMNA P02545 1/20 0.35
CA3 P07451 1/20 0.35
CA4 P22748 1/20 0.35
CA6 P23280 1/20 0.35
CA5A P35218 1/20 0.35
CA7 P43166 1/20 0.35
MCL1 Q07820 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzofuran SCHEMBL28850951 0.84 CYP2A6 (0.48) CYP2A6MAOBMAOAFTOKMT2A
SCHEMBL31681671 0.83 MAOB (0.44) CYP2A6ALDH1A1MAOBMAOAFTO
Benzofuran SCHEMBL22129287 0.83 MAOB (0.44) CYP2A6ALDH1A1MAOBMAOAFTO
Benzofuran SCHEMBL28138699 0.82 CYP2A6 (0.47) CYP2A6MAOBMAOAFTOKMT2A
Benzofuran SCHEMBL28203046 0.82 CYP2A6 (0.47) CYP2A6MAOBMAOAFTOKMT2A
Benzofuran SCHEMBL27437267 0.82 CYP2A6 (0.47) CYP2A6MAOBMAOAFTOCTNNB1
Benzofuran SCHEMBL3160534 0.81
Benzofuran SCHEMBL5564 0.81
Benzofuran SCHEMBL29393518 0.81
Benzofuran SCHEMBL5834531 0.81 MAOA (0.46) CYP2A6MAOBMAOAFTOCTNNB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108164414-A The synthetic method of high-purity 2- (benzoyl) chlorobenzoyl chloride 江苏佳麦化工有限公司 2018-06-15 CN disclosed
CN-105646280-B Quinone derivative and electrophotographic photoreceptor 京瓷办公信息系统株式会社 2018-04-17 CN disclosed
CN-105646277-B Quinone derivative and electrophotographic photoreceptor 京瓷办公信息系统株式会社 2017-10-24 CN disclosed