Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 5/20 | 0.67 |
| ▸ | PRKACA | P17612 | 4/20 | 0.56 |
| ▸ | PRKACG | P22612 | 4/20 | 0.56 |
| ▸ | PRKACB | P22694 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GLI1 | P08151 | 1/20 | 0.38 |
| ▸ | GLI2 | P10070 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 3/20 | 0.38 |
| ▸ | DDO | Q99489 | 2/20 | 0.38 |
| ▸ | TYMP | P19971 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987496 | 0.80 | SRC (1.00) | SRCPRKACAPRKACGPRKACBPARP1 | |
| SCHEMBL24931754 | 0.80 | KDM4E (0.75) | SRCKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL17434450 | 0.75 | CA12 (0.54) | SRCKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7034913 | 0.74 | KDM4E (0.53) | SRCPRKACAKDM4EALDH1A1HPGD | |
| SCHEMBL8142797 | 0.74 | KDM4E (0.58) | KDM4EALDH1A1HPGDSMN1; SMN2CA12 | |
| SCHEMBL3426314 | 0.74 | KDM4E (0.53) | SRCKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3669922 | 0.74 | GRIN2D (0.54) | KDM4EALDH1A1HPGDSMN1; SMN2CA12 | |
| SCHEMBL7984052 | 0.74 | SRC (0.71) | SRCPRKACAPRKACGPRKACBKDM4E | |
| SCHEMBL3883791 | 0.73 | SRC (1.00) | SRCPRKACAPRKACGPRKACBGPR35 | |
| SCHEMBL13671666 | 0.72 | SRC (0.44) | SRCKDM4EALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104884460-B | 2-substituted Cephem compounds | 葛兰素集团有限公司 | 2017-11-03 | — | — | CN | disclosed |