Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 6/20 | 0.60 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | F11 | P03951 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28188973 | 0.88 | NOTUM (0.60) | NOTUMF2ALDH1A1KMT2AMEN1 | |
| SCHEMBL16754039 | 0.84 | NOTUM (0.55) | NOTUMALDH1A1KMT2AMEN1POLB | |
| SCHEMBL11117017 | 0.78 | NOTUM (0.56) | NOTUMF2ALDH1A1KMT2AMEN1 | |
| SCHEMBL6077365 | 0.78 | NOTUM (0.51) | NOTUMALDH1A1KMT2AMEN1POLB | |
| SCHEMBL6078473 | 0.78 | NOTUM (0.51) | NOTUMALDH1A1KMT2AMEN1POLB | |
| SCHEMBL28538180 | 0.76 | NOTUM (0.49) | NOTUMALDH1A1KMT2AMEN1POLB | |
| SCHEMBL22636958 | 0.76 | ALDH1A1 (0.56) | NOTUMF2ALDH1A1KMT2APOLB | |
| SCHEMBL21776884 | 0.75 | NOTUM (1.00) | NOTUM | |
| SCHEMBL16335028 | 0.75 | ALDH1A1 (0.60) | ALDH1A1GPR119KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL28025989 | 0.73 | NOTUM (0.65) | NOTUMF2ALDH1A1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107501198-A | Sulfoxide tetranitroazole derivative and preparation method and application | 南京农业大学 | 2017-12-22 | — | — | CN | disclosed |