Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | SLC6A19 | Q695T7 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28192254 | 0.86 | SMN1; SMN2 (0.43) | SMN1; SMN2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL28191630 | 0.81 | SMN1; SMN2 (0.52) | SMN1; SMN2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL18039480 | 0.80 | SMN1; SMN2 (0.48) | SMN1; SMN2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL18039584 | 0.77 | NPC1 (0.48) | SMN1; SMN2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL28192167 | 0.76 | SMN1; SMN2 (0.38) | SMN1; SMN2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL28854135 | 0.74 | SMN1; SMN2 (0.43) | SMN1; SMN2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL28192204 | 0.74 | SMN1; SMN2 (0.39) | SMN1; SMN2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL28192182 | 0.73 | SMN1; SMN2 (0.43) | SMN1; SMN2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL28954481 | 0.72 | PTGDR2 (0.43) | SMN1; SMN2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL28191537 | 0.71 | SMN1; SMN2 (0.37) | SMN1; SMN2MEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107406427-A | Alkynyl alcohols and methods of use thereof | 豪夫迈·罗氏有限公司 | 2017-11-28 | — | — | CN | disclosed |