SCHEMBL28854192

SCHEMBL28854192

O=C1c2c(Cl)c(Cl)c(Cl)c(Cl)c2C(=O)N1OCC(O)CO

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
KMT2A Q03164 1/20 0.32
NR1H3 Q13133 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28854193 0.73 CA1 (0.37) KMT2A
SCHEMBL26249820 0.72 POLB (0.61) POLBSMN1; SMN2KMT2A
SCHEMBL6526529 0.72 POLB (0.61) POLBSMN1; SMN2KMT2A
SCHEMBL25427034 0.71 SMN1; SMN2 (0.35) POLBSMN1; SMN2KMT2A
SCHEMBL28006864 0.71 ALOX12 (0.35) POLBSMN1; SMN2KMT2A
SCHEMBL28334287 0.70 POLB (0.48) POLBSMN1; SMN2KMT2A
SCHEMBL8997256 0.63 CYP1A2 (0.40) KMT2A
SCHEMBL13479724 0.62 NR1H3 (0.39) NR1H3
SCHEMBL529416 0.62 POLB (0.70) POLBSMN1; SMN2KMT2A
SCHEMBL6321661 0.61 MAPT (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107431248-A Additive for nonaqueous electrolyte solution, and electricity storage device 住友精化株式会社 2017-12-01 CN disclosed