Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | CTSC | P53634 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.42 |
| ▸ | MGLL | Q99685 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28854336 | 1.00 | ELANE (0.49) | ELANEHDAC1CTSCMEN1KMT2A | |
| SCHEMBL20482434 | 0.90 | ELANE (0.54) | ELANECTSCKMT2ANPC1RAB9A | |
| SCHEMBL20482162 | 0.90 | ELANE (0.54) | ELANECTSCKMT2ANPC1RAB9A | |
| SCHEMBL168919 | 0.90 | ELANE (0.54) | ELANECTSCKMT2ANPC1RAB9A | |
| SCHEMBL5357416 | 0.85 | ELANE (0.49) | ELANECTSCRIPK1 | |
| SCHEMBL14994604 | 0.85 | ELANE (0.49) | ELANECTSCRIPK1 | |
| Hydrochloric Acid SCHEMBL1251429 | 0.83 | ELANE (0.48) | ELANECTSC | |
| Biphenyl SCHEMBL2308811 | 0.83 | ELANE (0.47) | ELANEHDAC1CTSCMEN1KMT2A | |
| SCHEMBL27623273 | 0.81 | ELANE (0.43) | ELANEMEN1KMT2AHPGDRIPK1 | |
| Trifluoroacetic Acid SCHEMBL5423648 | 0.81 | ELANE (0.47) | ELANECTSCNPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105130869-B | A kind of synthetic method of the ketone of Entresto intermediates (S) 5 (carbonyl of biphenyl 4) pyrrolidines 2 | 曾伟 | 2017-12-26 | — | — | CN | claimed |