Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | ABL1 | P00519 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | SCD | O00767 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24954540 | 1.00 | MAPT (0.67) | MAPTLMNAKMT2ACYP1A2MEN1 | |
| SCHEMBL24954027 | 0.89 | MAPT (0.51) | MAPTLMNAKMT2ACYP1A2MEN1 | |
| SCHEMBL24953674 | 0.89 | MAPT (0.51) | MAPTLMNAKMT2ACYP1A2MEN1 | |
| SCHEMBL24954265 | 0.89 | MAPT (0.51) | MAPTLMNAKMT2ACYP1A2MEN1 | |
| SCHEMBL24953697 | 0.88 | MAPT (0.69) | MAPTLMNAKMT2ACYP1A2MEN1 | |
| SCHEMBL24952901 | 0.80 | MAPT (0.41) | MAPTLMNAKMT2ACYP1A2L3MBTL1 | |
| SCHEMBL24952900 | 0.79 | MAPT (0.49) | MAPTLMNAKMT2ACYP1A2MEN1 | |
| SCHEMBL24953789 | 0.77 | MAPT (0.53) | MAPTLMNAKMT2ACYP1A2MEN1 | |
| SCHEMBL24953812 | 0.77 | MAPT (0.53) | MAPTLMNAKMT2ACYP1A2MEN1 | |
| SCHEMBL2753861 | 0.76 | LMNA (0.73) | MAPTLMNAKMT2ACYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114845709-A | MRGPRX2 antagonists for use in treating inflammatory disorders | 德米拉公司 | 2022-08-02 | — | — | CN | disclosed |