Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.32 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31461336 | 0.74 | MEN1 (0.55) | KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL1049879 | 0.74 | MEN1 (0.55) | KMT2AMEN1ALDH1A1GAA | |
| Phosphoric Acid SCHEMBL29008757 | 0.72 | MEN1 (0.46) | KMT2AMEN1ALDH1A1TDP1L3MBTL1 | |
| Iodide SCHEMBL27944610 | 0.72 | MEN1 (0.53) | KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL15108863 | 0.72 | ALDH1A1 (0.39) | KMT2AALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL28279986 | 0.71 | MEN1 (0.38) | KMT2AMEN1 | |
| SCHEMBL28972004 | 0.71 | MEN1 (0.40) | KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL29082977 | 0.67 | MEN1 (0.34) | KMT2AMEN1 | |
| SCHEMBL29066619 | 0.66 | NR4A2 (0.43) | KMT2AMEN1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL29170436 | 0.66 | NPSR1 (0.37) | KMT2AMEN1ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105733564-B | A kind of Ratiometric fluorescent probe sensitive Mitochondrially targeted pH and its preparation method and application | 郑州大学 | 2018-01-05 | — | — | CN | disclosed |