Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 3/20 | 0.41 |
| ▸ | CDK2 | P24941 | 3/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24696515 | 0.79 | MEN1 (0.46) | MEN1KMT2ACNR1CDK2PDGFRB | |
| SCHEMBL30041042 | 0.79 | MEN1 (0.46) | MEN1KMT2ACNR1CDK2PDGFRB | |
| SCHEMBL2466401 | 0.78 | IDO1 (0.56) | MEN1KMT2AIDO1CNR1PDGFRB | |
| SCHEMBL8541433 | 0.77 | CDK2 (0.45) | MEN1KMT2ACNR1CDK2CYP3A4 | |
| SCHEMBL27082784 | 0.77 | MAPT (0.46) | MEN1KMT2ACNR1CDK2KDM4E | |
| SCHEMBL15416944 | 0.76 | CDK2 (0.47) | MEN1KMT2ACDK2KDM4EALDH1A1 | |
| SCHEMBL20383160 | 0.75 | CYP3A4 (0.56) | IDO1JAK2CYP3A4ALDH1A1AGPAT2 | |
| SCHEMBL4602986 | 0.74 | AURKA (0.41) | MEN1KMT2AIDO1CDK2ALDH1A1 | |
| SCHEMBL30390867 | 0.74 | AURKA (0.41) | MEN1KMT2AIDO1CDK2ALDH1A1 | |
| SCHEMBL28196354 | 0.74 | NOTUM (0.44) | JAK2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104507923-B | Substituted pyrrole active agents as kinase inhibitors | 内尔维阿诺医学科学有限公司 | 2018-02-09 | — | — | CN | disclosed |