Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30390867 | 1.00 | AURKA (0.41) | AURKAKDRRAB9ASMN1; SMN2HPGD | |
| SCHEMBL29611794 | 0.86 | CD274 (0.39) | AURKAKDRRAB9ASMN1; SMN2TSHR | |
| Imidazole SCHEMBL16860237 | 0.83 | ALDH1A1 (0.41) | AURKAKDRRAB9ASMN1; SMN2HPGD | |
| SCHEMBL15416821 | 0.83 | KDR (0.47) | AURKAKDRCDK2NPC1ADRA1D | |
| SCHEMBL6285311 | 0.83 | AURKA (0.42) | AURKAKDRRAB9ATSHRCDK2 | |
| SCHEMBL5851492 | 0.81 | KDR (0.49) | AURKAKDRCDK2ADRA1DADRA1A | |
| SCHEMBL15416944 | 0.79 | CDK2 (0.47) | AURKAKDRRAB9ATSHRGAA | |
| SCHEMBL6285309 | 0.77 | MAPT (0.50) | AURKAKDRRAB9ASMN1; SMN2HPGD | |
| SCHEMBL29079111 | 0.74 | KDR (0.42) | AURKAKDRCDK2NPC1ADRA1D | |
| SCHEMBL28563542 | 0.74 | NPC1 (0.47) | AURKAKDRRAB9AHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105237466-B | A kind of method for synthesizing three substituted pyridine derivatives | 南阳师范学院 | 2017-08-25 | — | — | CN | claimed |
| CN-104163775-B | A kind of production method of o-methyl-phenyl-azanol | 盐城工学院 | 2017-04-05 | — | — | CN | claimed |
| CN-106187810-A | A kind of preparation method of o-methyl-phenyl-azanol | 安徽国星生物化学有限公司 | 2016-12-07 | — | — | CN | claimed |
| CN-105646276-A | Preparation method of o-methyl phenyl hydroxylamine | 安徽国星生物化学有限公司 | 2016-06-08 | — | — | CN | claimed |
| CN-104557712-A | Preparation methods of aromatic hydroxylamine compound and N-aromatic acylated hydroxylamine compound | NUTRICHEM CO LTD | 2015-04-29 | — | — | CN | claimed |
| CN-104163775-A | Method for producing O-methyl phenyl hydroxylamine | YANCHENG INST TECHNOLOGY | 2014-11-26 | — | — | CN | claimed |
| JP-1268791-A | — | — | None | — | — | JP | disclosed |
| US-11939291-B2 | GRP94 selective inhibitors and uses thereof | UNIVERSITY OF KANSAS (US) | 2024-03-26 | — | — | US | disclosed |
| WO-2023224560-A1 | ENZYMES AND USES IN BIOCATALYTIC HALOGENATION OF N-HETEROARYLS THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2023-11-23 | — | — | WO | disclosed |
| CN-109791357-B | Photosensitive resin composition, cured product and image display device | 三菱化学株式会社 | 2023-01-10 | — | — | CN | disclosed |
| CN-109923475-B | Photosensitive coloring composition, cured product, coloring spacer and image display device | 三菱化学株式会社 | 2022-12-02 | — | — | CN | disclosed |
| CN-114545737-A | Photosensitive coloring composition for colored spacer, cured product, colored spacer, and image display device | 三菱化学株式会社 | 2022-05-27 | — | — | CN | disclosed |
| CN-114450630-A | Photosensitive resin composition, cured product, partition wall, organic electroluminescent element, color filter, and image display device | 三菱化学株式会社 | 2022-05-06 | — | — | CN | disclosed |
| WO-2003087090-A2 | NOVEL HETEROARYL ALKYLAMIDE DERIVATIVES USEFUL AS BRADYKININ RECEPTOR MODULATORS | ORTHO-MCNEIL PHARMACEUTICAL,INC. (US) | 2003-10-23 | — | — | WO | disclosed |
| US-6610730-B2 | Viricides; protease inbhibitor | AGOURON PHARMACEUTICALS, INC. | 2003-08-26 | — | — | US | disclosed |
| CN-1431995-A | Antipicornaviral compounds and compsns. their pharmaceutical uses, and materials for their synthesis | AGOURON PHARMA (US) | 2003-07-23 | — | — | CN | disclosed |
| EP-1274682-A2 | ANTIPICORNAVIRAL COMPOUNDS AND COMPOSITIONS, THEIR PHARMACEUTICAL USES, AND MATERIALS FOR THEIR SYNTHESIS | AGOURON PHARMACEUTICALS, INC. (US) | 2003-01-15 | — | — | EP | disclosed |
| US-20020006943-A1 | Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis | AGOURON PHARMACEUTICALS, INC. | 2002-01-17 | — | — | US | disclosed |
| WO-2001079167-A2 | ANTIPICORNAVIRAL COMPOUNDS AND COMPOSITIONS, THEIR PHARMACEUTICAL USES, AND MATERIALS FOR THEIR SYNTHESIS | AGOURON PHARMACEUTICALS, INC. (US) | 2001-10-25 | — | — | WO | disclosed |
| JP-H01268791-A | COMPOSITION FOR INHIBITION OF CORROSION IN FUEL SYSTEM, AND METHOD FOR USE AND PREPARATION THEREOF | PETROLITE CORP | 1989-10-26 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11939291-B2 | GRP94 selective inhibitors and uses thereof | GRPR, HSP90B1, HSPE1 | AURKA 2435/4885KDR 872/4885RAB9A 1699/4885 |
| US-20020006943-A1 | Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis | PRCP, RNPEP, SERPINB1 | AURKA 2705/4885KDR 4508/4885RAB9A 2774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.