SCHEMBL28855849

SCHEMBL28855849

NC(=O)C1CC1c1cc(Cl)cc(Cl)c1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 7/20 0.49
GRM4 Q14833 2/20 0.46
FAAH O00519 3/20 0.40
SIRT2 Q8IXJ6 1/20 0.36
SIRT1 Q96EB6 1/20 0.36
AURKA O14965 1/20 0.36
LCK P06239 1/20 0.36
FYN P06241 1/20 0.36
IGF1R P08069 1/20 0.36
MET P08581 1/20 0.36
KIT P10721 1/20 0.36
FGFR2 P21802 1/20 0.36
EPHA2 P29317 1/20 0.36
LTK P29376 1/20 0.36
AXL P30530 1/20 0.36
FLT3 P36888 1/20 0.36
MST1R Q04912 1/20 0.36
ALDH1A1 P00352 1/20 0.36
FFAR1 O14842 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29302327 0.88 SLC9A1 (0.43) SLC9A1GRM4FAAHAURKALCK
SCHEMBL30641928 0.83 SLC9A1 (0.41) SLC9A1GRM4FAAHAURKALCK
SCHEMBL8150013 0.82 FFAR1 (0.49) SLC9A1GRM4ALDH1A1FFAR1
SCHEMBL6994971 0.82 FFAR1 (0.49) SLC9A1GRM4ALDH1A1FFAR1
SCHEMBL6994974 0.82 FFAR1 (0.49) SLC9A1GRM4ALDH1A1FFAR1
SCHEMBL8150011 0.82 FFAR1 (0.49) SLC9A1GRM4ALDH1A1FFAR1
SCHEMBL24737578 0.82 SLC9A1 (0.71) SLC9A1ALDH1A1
SCHEMBL24737580 0.82 SLC9A1 (0.71) SLC9A1ALDH1A1
SCHEMBL24737867 0.82 SLC9A1 (0.71) SLC9A1ALDH1A1
SCHEMBL15542072 0.82 SLC9A1 (0.71) SLC9A1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118044519-A Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2024-05-17 CN disclosed
CN-117603014-A Meta-diamide compounds for controlling invertebrate pests FMC公司 2024-02-27 CN disclosed
CN-110072842-B Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2024-02-02 CN disclosed
CN-117098750-A Molecules having pesticidal utility, and intermediates and methods related thereto 科迪华农业科技有限责任公司 2023-11-21 CN disclosed
EP-4183766-A1 INTERMEDIATES FOR THE PREPARATION OF META-DIAMIDE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS FMC Corporation (US) 2023-05-24 EP disclosed
EP-3887354-B1 META-DIAMIDE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS FMC CORP (US) 2023-01-04 EP disclosed
CN-107529748-A Molecule with desinsection effectiveness, and relative intermediate, composition and method 美国陶氏益农公司 2018-01-02 CN disclosed