SCHEMBL28855893

SCHEMBL28855893

CCOC(=O)CCCCC(=O)Nc1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.70
HPGD P15428 1/20 0.62
HDAC1 Q13547 15/20 0.60
HDAC4 P56524 14/20 0.60
HDAC11 Q96DB2 14/20 0.60
HDAC8 Q9BY41 14/20 0.60
HDAC6 Q9UBN7 14/20 0.60
HDAC5 Q9UQL6 14/20 0.60
HDAC3 O15379 14/20 0.60
HDAC2 Q92769 14/20 0.60
HDAC7 Q8WUI4 13/20 0.60
HDAC9 Q9UKV0 13/20 0.60
HDAC10 Q969S8 13/20 0.60
KDM4E B2RXH2 1/20 0.59
BRD4 O60885 1/20 0.59
NCOR1 O75376 1/20 0.59
NR1I2 O75469 1/20 0.59
EGFR P00533 1/20 0.59
CYP3A4 P08684 1/20 0.59
LTA4H P09960 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3067050 0.97 HPGD (0.66) ALDH1A1HPGDHDAC1HDAC4HDAC11
SCHEMBL18286402 0.91 MAPT (0.64) ALDH1A1HPGDHDAC1HDAC4HDAC11
SCHEMBL5592685 0.90 MAPT (0.63) ALDH1A1HPGD
SCHEMBL1233439 0.90 HDAC1 (0.66) ALDH1A1HPGDHDAC1HDAC4HDAC11
SCHEMBL18256373 0.87 KLK7 (0.57) ALDH1A1HPGDHDAC1HDAC4HDAC11
SCHEMBL12744125 0.87 HDAC1 (0.57) ALDH1A1HPGDHDAC1HDAC4HDAC11
SCHEMBL18256371 0.86 KLK7 (0.56) ALDH1A1HDAC1HDAC4HDAC11HDAC8
SCHEMBL16409794 0.85 EPHX2 (0.66) HPGDHDAC1HDAC4HDAC11HDAC8
SCHEMBL541048 0.85 LMNA (0.68) ALDH1A1HDAC1HDAC4HDAC11HDAC8
SCHEMBL313148 0.84 HDAC4 (0.68) HDAC1HDAC4HDAC11HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112574054-B Efficient nitriding reagent and application thereof 北京大学 2022-10-14 CN disclosed