Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 16/20 | 0.54 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL287532 | 0.89 | GABRA5 (0.52) | GABRA5 | |
| SCHEMBL288200 | 0.88 | GABRA5 (0.66) | GABRA5ITGA5 | |
| SCHEMBL288742 | 0.85 | GABRA5 (0.65) | GABRA5ITGA5 | |
| SCHEMBL1776592 | 0.85 | ITGA5 (0.61) | GABRA5ITGA5GABRA1 | |
| SCHEMBL289211 | 0.83 | GABRA5 (0.57) | GABRA5ITGA5GABRA1 | |
| SCHEMBL288771 | 0.81 | GABRA5 (0.55) | GABRA5ITGA5GABRA1 | |
| SCHEMBL288662 | 0.81 | GABRA5 (0.68) | GABRA5ITGA5GABRA1 | |
| SCHEMBL287977 | 0.80 | GABRA5 (0.55) | GABRA5ITGA5GABRA1 | |
| SCHEMBL288663 | 0.80 | GABRA5 (0.54) | GABRA5ITGA5GABRA1 | |
| SCHEMBL288229 | 0.79 | GABRA5 (0.70) | GABRA5ITGA5GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427456-A1 | ISOXAZOLE-PYRIDINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2012-03-14 | — | — | EP | disclosed |